December 2007. Volume 3. Number 4

In children with idiopathic thrombocytopenic purpura: is early treatment better than watchful waiting without specific therapy?

 
 
 
 
 
 
 
 
 
 
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ED | Editorial

Author: Monteagudo Montesinos E1.
1 Jefe de Sección de Pediatrí­a. Hospital Infantil La Fe. Valencia .. España.
Correspondence: Emilio Monteagudo Montesinos. Email: emonteagudo@aehh.org
Publication date: 01/12/2007

How to cite this article

Monteagudo Montesinos E. ¿Tratamiento desde el inicio o actitud expectante en el niño con púrpura trombopénica idiopática aguda ?. Evid Pediatr. 2007;3:89.

ED | Editorial

Author: Monteagudo Montesinos E1.
1 Jefe de Sección de Pediatrí­a. Hospital Infantil La Fe. Valencia .. España.
Correspondence: Emilio Monteagudo Montesinos. Email: emonteagudo@aehh.org
Publication date: 01/12/2007

How to cite this article

Monteagudo Montesinos E. ¿Tratamiento desde el inicio o actitud expectante en el niño con púrpura trombopénica idiopática aguda ?. Evid Pediatr. 2007;3:89.

References

  1. Sartorius JA. Steroid treatment of idiopathic thrombocytopenic purpura in children. Preliminary results of a randomized cooperative study. Am J Pediatr Hematol Oncol. 1984;6:165-9.
  2. Imbach P, Barandun S, d'Apuzzo V, Baumgartner C, Hirt A, Morell A, et al. High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet. 1981;1:1228-31.
  3. Imbach P, Wagner HP, Berchtold W, Gaedicke G, Hirt A, Joller P, et al. Intravenous immunoglobulin versus oral corticosteroids in acute immune thrombocytopenic purpura in childhood. Lancet. 1985;2:464-8.
  4. Salama A, Kiefel V, Amberg R, Mueller-Eckhardt C. Treatment of autoimmune thrombocytopenic purpura with rhesus antibodies (anti-Rh0(D)]. Blut. 1984;49:29-35.
  5. Blanchette VS, Luke B, Andrew M, Sommerville-Nielsen S, Barnard D, de VB, et al. A prospective, randomized trial of high-dose intravenous immune globulin G therapy, oral prednisone therapy, and no therapy in childhood acute immune thrombocytopenic purpura. J Pediatr. 1993;123:989-95.
  6. Blanchette V, Imbach P, Andrew M, Adams M, McMillan J, Wang E, et al. Randomised trial of intravenous immunoglobulin G, intravenous anti-D, and oral prednisone in childhood acute immune thrombocytopenic purpura. Lancet. 1994;344:703-7.
  7. Albayrak D, Islek I, Kalayci AG, Gurses N. Acute immune thrombocytopenic purpura: a comparative study of very high oral doses of methylprednisolone and intravenously administered immune globulin. J Pediatr. 1994;125(6 Pt 1):1004-7.
  8. Ancona KG, Parker RI, Atlas MP, Prakash D. Randomized trial of high-dose methylprednisolone versus intravenous immunoglobulin for the treatment of acute idiopathic thrombocytopenic purpura in children. J Pediatr Hematol Oncol. 2002;24:540-4.
  9. Benesch M, Kerbl R, Lackner H, Berghold A, Schwinger W, Triebl-Roth K, et al. Low-dose versus high-dose immunoglobulin for primary treatment of acute immune thrombocytopenic purpura in children: results of a prospective, randomized single-center trial. J Pediatr Hematol Oncol. 2003;25:797-800.
  10. Carcao MD, Zipursky A, Butchart S, Leaker M, Blanchette VS. Short-course oral prednisone therapy in children presenting with acute immune thrombocytopenic purpura (ITP). Acta Paediatr Suppl. 1998;424:71-4.
  11. Duru F, Fisgin T, Yarali N, Kara A. Clinical course of children with immune thrombocytopenic purpura treated with intravenous immunoglobulin G or megadose methylprednisolone or observed without therapy. Pediatr Hematol Oncol. 2002;19:219-25.
  12. El Alfy MS, Mokhtar GM, El-Laboudy MA, Khalifa AS. Randomized trial of anti-D immunoglobulin versus low-dose intravenous immunoglobulin in the treatment of childhood chronic idiopathic thrombocytopenic purpura. Acta Haematol. 2006;115:46-52.
  13. Erduran E, Aslan Y, Gedik Y, Orhan F. A randomized and comparative study of intravenous immunoglobulin and mega dose methylprednisolone treatments in children with acute idiopathic thrombocytopenic purpura. Turk J Pediatr. 2003;45:295-300.
  14. Fujisawa K, Iyori H, Ohkawa H, Konishi S, Bessho F, Shirahata A, et al. A prospective, randomized trial of conventional, dose-accelerated corticosteroids and intravenous immunoglobulin in children with newly diagnosed idiopathic thrombocytopenic purpura. Int J Hematol. 2000;72:376-83.
  15. Ozsoylu S, Sayli TR, Ozturk G. Oral megadose methylprednisolone versus intravenous immunoglobulin for acute childhood idiopathic thrombocytopenic purpura. Pediatr Hematol Oncol. 1993;10:317-21.
  16. Rosthoj S, Nielsen S, Pedersen FK. Randomized trial comparing intravenous immunoglobulin with methylprednisolone pulse therapy in acute idiopathic thrombocytopenic purpura. Danish I.T.P. Study Group. Acta Paediatr. 1996;85:910-5.
  17. Tarantino MD, Young G, Bertolone SJ, Kalinyak KA, Shafer FE, Kulkarni R, et al. Single dose of anti-D immune globulin at 75 microg/kg is as effective as intravenous immune globulin at rapidly raising the platelet count in newly diagnosed immune thrombocytopenic purpura in children. J Pediatr. 2006;148:489-94.
  18. George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood. 1996;88:3-40.
  19. Eden OB, Lilleyman JS. Guidelines for management of idiopathic thrombocytopenic purpura. The British Paediatric Haematology Group. Arch Dis Child. 1992;67:1056-8.
  20. De MD, Del PD, Del Vecchio GC, Jankovic M, Arrighini A, Giordano P, et al. Acute childhood idiopathic thrombocytopenic purpura: AIEOP consensus guidelines for diagnosis and treatment.Associazione Italiana di Ematologia e Oncologia Pediatrica. Haematologica. 2000;85:420-4.
  21. [Protocol for the study and treatment of immune thrombocytopenic purpura. The Working Group of the Sociedad Espanola de Hematologia Pediatrica]. An Esp Pediatr. 1996;44:623-31.
  22. Corrigan JJ, Jr. Treatment dilemma in childhood idiopathic thrombocytopenic purpura. Lancet. 1997;350:602-3.
  23. George JN. Initial management of immune thrombocytopenic purpura in children: is supportive counseling without therapeutic intervention sufficient? J Pediatr. 2000;137:598-600.
  24. Lilleyman JS. Intracranial haemorrhage in idiopathic thrombocytopenic purpura. Paediatric Haematology Forum of the British Society for Haematology. Arch Dis Child. 1994;71:251-3.
  25. Lilleyman JS. Management of childhood idiopathic thrombocytopenic purpura. Br J Haematol. 1999;105:871-5.
  26. Medeiros D, Buchanan GR. Current controversies in the management of idiopathic thrombocytopenic purpura during childhood. Pediatr Clin North Am. 1996;43:757-72.
  27. Modak SI, Bussel JB. Treatment of children with immune thrombocytopenic purpura: are we closer to resolving the dilemma? J Pediatr. 1998;133:313-4.
  28. Nugent DJ. Immune thrombocytopenic purpura: why treat? J Pediatr. 1999;134:3-4.
  29. Butros LJ, Bussel JB. Intracranial hemorrhage in immune thrombocytopenic purpura: a retrospective analysis. J Pediatr Hematol Oncol. 2003;25:660-4.
  30. Dickerhoff R, von RA. The clinical course of immune thrombocytopenic purpura in children who did not receive intravenous immunoglobulins or sustained prednisone treatment. J Pediatr. 2000;137:629-32.
  31. Iyori H, Bessho F, Ookawa H, Konishi S, Shirahata A, Miyazaki S, et al. Intracranial hemorrhage in children with immune thrombocytopenic purpura. Japanese Study Group on childhood ITP. Ann Hematol. 2000;79:691-5.
  32. Kuhne T, Imbach P, Bolton-Maggs PH, Berchtold W, Blanchette V, Buchanan GR. Newly diagnosed idiopathic thrombocytopenic purpura in childhood: an observational study. Lancet. 2001;358:2122-5.
  33. Medeiros D, Buchanan GR. Major hemorrhage in children with idiopathic thrombocytopenic purpura: immediate response to therapy and long-term outcome. J Pediatr. 1998;133:334-9.
  34. Roganovic J, Letica-Crepulja M. Idiopathic thrombocytopenic purpura: a 15-year natural history study at the Children's Hospital Rijeka, Croatia. Pediatr Blood Cancer. 2006;47(5 Suppl):662-4.
  35. Treutiger I, Rajantie J, Zeller B, Henter JI, Elinder G, Rosthoj S, et al. Does treatment of newly diagnosed idiopathic thrombocytopenic purpura reduce morbidity? Arch Dis Child. 2007;92:704-7.
  36. Perdikidis Olivieri L, Gonzalez de Dios J. El tratamiento precoz de la púrpura trombopénica idiopática no reduce la morbilidad y no parece tener impacto sobre la evolución a largo plazo de la misma. Evid Pediatr. 2007;3:98.
01/12/2007

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