December 2007. Volume 3. Number 4

In healthy children aged 12-23 months a tetravalent measles-mumps-rubella-varicella vaccine co-administered with a booster dose of a combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b conjugate vaccine has similar immunogenicity as if administered alone

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Zepp F, Behre U, Kindler K, Laakmann KH, Pankow-Culot H, Mannhardt-Laakmann W, et al. Immunogenicity and safety of a tetravalent measles-mumps-rubella-varicella vaccine co-administered with a booster dose of a combined diphtheria-tetanus-acellular pertussis-hepatitis b-inactivated poliovirus-haemophilus influenzae type b conjugate vaccine in healthy children aged 12–23 months. Eur J Pediatr. 2007;166:857-64
Reviewers: Chalco Orrego JP1, Rojas Galarza RA2, Bada Mancilla CA3.
1Pediatra independiente. Lima. Perú.
2Unidad de Emergencia. Instituto Nacional de Salud del Niño. Lima (Perú). España.
3Servicio de Urgencias. Hospital de Emergencias Pediátricas. Lima. Perú.
Correspondence: Juan Pablo Chalco Orrego. Email: jpcho33@yahoo.com
Reception date: 2/11/2007
Acceptance date: 11/11/2007
Publication date: 01/12/2007

Abstract

How to cite this article

Chalco Orrego JP, Rojas Galarza RA, Bada Mancilla CA. La vacuna tetravalente de sarampión-parotiditis-rubéola-varicela parece tener similar inmunogenicidad si se aplica sola o junto a una dosis de refuerzo de vacuna conjugada difteria-tétanos-pertusis acelular-hepatitis b-poliovirus inactivado-haemophilus influenzae tipo b en niños sanos de 12-23 mesesEvid Pediatr. 2007;3:97.

AVC | Critically appraised articles

Zepp F, Behre U, Kindler K, Laakmann KH, Pankow-Culot H, Mannhardt-Laakmann W, et al. Immunogenicity and safety of a tetravalent measles-mumps-rubella-varicella vaccine co-administered with a booster dose of a combined diphtheria-tetanus-acellular pertussis-hepatitis b-inactivated poliovirus-haemophilus influenzae type b conjugate vaccine in healthy children aged 12–23 months. Eur J Pediatr. 2007;166:857-64
Reviewers: Chalco Orrego JP1, Rojas Galarza RA2, Bada Mancilla CA3.
1Pediatra independiente. Lima. Perú.
2Unidad de Emergencia. Instituto Nacional de Salud del Niño. Lima (Perú). España.
3Servicio de Urgencias. Hospital de Emergencias Pediátricas. Lima. Perú.
Correspondence: Juan Pablo Chalco Orrego. Email: jpcho33@yahoo.com
Reception date: 2/11/2007
Acceptance date: 11/11/2007
Publication date: 01/12/2007

How to cite this article

Chalco Orrego JP, Rojas Galarza RA, Bada Mancilla CA. La vacuna tetravalente de sarampión-parotiditis-rubéola-varicela parece tener similar inmunogenicidad si se aplica sola o junto a una dosis de refuerzo de vacuna conjugada difteria-tétanos-pertusis acelular-hepatitis b-poliovirus inactivado-haemophilus influenzae tipo b en niños sanos de 12-23 mesesEvid Pediatr. 2007;3:97.

References

  1. Vesikari T, Sadzot-Delvaux C, Rentier B, Gershon A. Increasing coverage and efficiency of measles, mumps, and rubella vaccine and introducing universal varicella vaccination in Europe: a role for the combined vaccine. Pediatr Infect Dis J. 2007;26:632-8.
  2. Hammerschmidt T, Bisanz H, Wutzler P. Universal mass vaccination against varicella in Germany using an MMRV combination vaccine with a two-dose schedule: An economic analysis. Vaccine. 2007;25:7307-12.
  3. Horne AD, Lachenbruch PA, Getson PR, Hsu HS. Analysis of studies to evaluate immune response to combination vaccines. Clin Infect Dis. 2001;33:S306-11.
  4. US Food and Drug Administration, Center for Biologics Evaluation and Research. Guidance for industry for the evaluation of combination vaccines for preventable diseases: production, testing and clinical studies. Rockville, MD: 1997 [en línea][consultado : 2-XI-2007]. Disponible en: http://www.fda.gov/cber/gdlns/combvacc.txt
  5. Hudgens MG, Gilbert PB, Self SG. Endpoints in vaccine trials. Stat Methods Med Res. 2004;13:89-114.
01/12/2007

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