March 2016. Volume 12. Number 1

Inconclusive effect of glycerine laxatives for improving feeding tolerance in preterm newborns

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Livingston MH, Shawyer AC, Rosenbaum PL, Williams C, Jones SA, Walton JM. Glycerin enemas and suppositories in premature infants: a meta-analysis. Pediatrics. 2015;135:1093-106.
Reviewers: Carvajal Encina F1, Perdikidis Olivieri L2.
1UCIN Hospital de La Serena y Escuela de Medicina Universidad Católica del Norte. La Serena. Elqui. Chile.
2EAP Juncal. Torrejón de Ardoz. Madrid. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 14/01/2016
Acceptance date: 03/02/2016
Publication date: 10/02/2016

Abstract

Authors conclusions:the evidence for the use of glycerin enemas or suppositories in premature infants in inconclusive. Meta-analyzed data suggest that treatment may be associated with increased risk of necrotizing enterocolitis.

Reviewer’s commentary:meta-analysis of the data suggests that the evaluated intervention has no consistent effect on the evacuation of meconium, the transition to full enteral feeding or mortality. There may be an increased risk of NEC, so we can not recommend its use because of the potential risk of harm associated.

How to cite this article

Carvajal Encina F, Perdikidis Olivieri L. Dudoso efecto de los laxantes de glicerina en prematuros sobre la tolerancia alimentaria. Evid Pediatr. 2016;12:9.

AVC | Critically appraised articles

Livingston MH, Shawyer AC, Rosenbaum PL, Williams C, Jones SA, Walton JM. Glycerin enemas and suppositories in premature infants: a meta-analysis. Pediatrics. 2015;135:1093-106.
Reviewers: Carvajal Encina F1, Perdikidis Olivieri L2.
1UCIN Hospital de La Serena y Escuela de Medicina Universidad Católica del Norte. La Serena. Elqui. Chile.
2EAP Juncal. Torrejón de Ardoz. Madrid. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 14/01/2016
Acceptance date: 03/02/2016
Publication date: 10/02/2016

How to cite this article

Carvajal Encina F, Perdikidis Olivieri L. Dudoso efecto de los laxantes de glicerina en prematuros sobre la tolerancia alimentaria. Evid Pediatr. 2016;12:9.

References

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10/02/2016

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