Authors’s conclusions: the parotitis component of the MMR vaccine appears to be significantly less immunogenic than that of measles, with a higher decrease in antibody levels. There is a significant increase in the T cell response to mumps and measles, although for parotitis, this increase is small. The biological relevance of this difference is not clear.
Reviewer’s commentary: the small sample size and the origin of the cohort raise questions about the representativeness of the sample, although it is highly likely that in our environment a similar phenomenon occurs, since it is now a very common occurrence the diagnosis of adolescents with mumps. Revaccination should therefore be considered to improve protection, at least in the case of epidemic outbreaks.