March 2009. Volume 5. Number 1

Caffeine intake during pregnancy increases the risk of low birthweight infants

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. CARE Study Group. BMJ. 2008;337:a2332
Reviewers: Puebla Molina SF1, Bonillo Perales A2.
1Departamento de Pediatría Clínica Alemana de Temuco. Magíster en Epidemiología Clínica. CIGES y Departamentos de Pediatría y Salud Pública. Universidad de la Frontera y Hospital Dr. Hernán Henríquez Aravena. Chile.
2Hospital Torrecárdenas. Almería. España.
Correspondence: Sergio Francisco Puebla Molina. Email: sepumo@gmail.com
Reception date: 03/02/2009
Acceptance date: 23/02/2009
Publication date: 24/02/2009

Abstract

Authors' conclusions: Caffeine intake during pregnancy > 200 mg / day increases the risk of low birthweight.

Reviewers' comantary: Observational cohort study of a large sample size, controlling confounding variables that may affect fetal growth and birth weight. It demonstrates an association between LBW and intake of caffeine from values as low as 30 mg / day. This association appears to exist throughout the pregnancy. It is highlighted the weakness of previous studies that consider caffeine intake linked only to coffee and cola drinks, which could underestimate the real impact of caffeine on fetal growth.

How to cite this article

Puebla Molina S, Bonillo Perales A. La ingesta de cafeína durante el embarazo aumenta el riesgo de recién nacidos de bajo peso. Evid Pediatr. 2009;5:24.

AVC | Critically appraised articles

Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. CARE Study Group. BMJ. 2008;337:a2332
Reviewers: Puebla Molina SF1, Bonillo Perales A2.
1Departamento de Pediatría Clínica Alemana de Temuco. Magíster en Epidemiología Clínica. CIGES y Departamentos de Pediatría y Salud Pública. Universidad de la Frontera y Hospital Dr. Hernán Henríquez Aravena. Chile.
2Hospital Torrecárdenas. Almería. España.
Correspondence: Sergio Francisco Puebla Molina. Email: sepumo@gmail.com
Reception date: 03/02/2009
Acceptance date: 23/02/2009
Publication date: 24/02/2009

How to cite this article

Puebla Molina S, Bonillo Perales A. La ingesta de cafeína durante el embarazo aumenta el riesgo de recién nacidos de bajo peso. Evid Pediatr. 2009;5:24.

References

  1. Boylan SM, Cade JE, Kirk SFL, Greenwood DC, White KLM, Shires S, et al. Assessing caffeine exposure in pregnant women. Br J Nutr 2008;100:875-82.
  2. Perinatal Institute, Birmingham. Gestation Network [en línea][fecha de consulta: 23-II-2009. Disponible en: http://www.gestation.net/
  3. Committee on Toxicity. COT statement on the reproductive effects of caffeine. London: Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment, 2001. [en línea][fecha de consulta: 23-II-2009]. Disponible en: http://cot.food.gov.uk/cotstatements/cotstatementsyrs/cotstatements2001/caffeine
  4. Vik T, Bakketeig LS, Trygg KU, Lund-Larsen K, Jacobsen G. High caffeine consumption in the third trimester of pregnancy: genderspecific effects on fetal growth. Paediatr Perinat Epidemiol 2003;17:324-31.
24/02/2009

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