March 2011. Volume 7. Number 1

Syncitial respiratory virus is one of the major cause of child mortality and morbidity associates to lower respiratory tract infections in the world

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010;375:1545-55.
Reviewers: Chalco Orrego JP1, Bernaola Aponte G2.
1Pediatra independiente. Madrid. España.
2Máster en Epidemiología Clínica. Servicio de Pediatría. Hospital Suárez Angamos. Lima. Perú.
Correspondence: Juan Pablo Chalco Orrego. Email: jpcho33@yahoo.com
Reception date: 18/11/2010
Acceptance date: 02/12/2010
Publication date: 09/12/2010

Abstract

Authors' conclusions: respiratory syncitial virus (RSV) is the most common cause of childhood Acute Lower Respiratory Infections (ALRI) and a major cause of admission to hospital as a result of severe ALRI. Mortality data suggest that RSV is an important cause of death in childhood from ALRI, after pneumococcal pneumonia and Haemophilus influenzae type b.

Reviewers' commentary: despite an uncertainty level in estimates we can´t deny the impact of RSV infections on hospitalizations and mortality in children. National or regional reliable data of incidence and mortality are required awaiting a safe and effective vaccine against RSV.

How to cite this article

Chalco Orrego JP, Bernaola Aponte G. El virus sincitial respiratorio es uno de los principales responsables de la morbimortalidad en la infancia asociada con infecciones del tracto respiratorio bajo en el mundo. Evid Pediatr. 2011;7:6.

AVC | Critically appraised articles

Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010;375:1545-55.
Reviewers: Chalco Orrego JP1, Bernaola Aponte G2.
1Pediatra independiente. Madrid. España.
2Máster en Epidemiología Clínica. Servicio de Pediatría. Hospital Suárez Angamos. Lima. Perú.
Correspondence: Juan Pablo Chalco Orrego. Email: jpcho33@yahoo.com
Reception date: 18/11/2010
Acceptance date: 02/12/2010
Publication date: 09/12/2010

How to cite this article

Chalco Orrego JP, Bernaola Aponte G. El virus sincitial respiratorio es uno de los principales responsables de la morbimortalidad en la infancia asociada con infecciones del tracto respiratorio bajo en el mundo. Evid Pediatr. 2011;7:6.

References

  1. World Health Organization. Acute Respiratory Infections (Update September 2009). 2009 [en línea] [fecha de consulta: 12-X-2010]. Disponible en: http://www.who.int/vaccine_research/diseases/ari/en/print.html
  2. Iwane MK, Edwards KM, Szilagyi PG, Walker FJ, Griffin MR, Weinberg GA, et al. Population-Based Surveillance for Hospitalizations Associated With Respiratory Syncytial Virus, Influenza Virus, and Parainfluenza Viruses Among Young Children. Pediatrics. 2004;113:1758-64.
  3. Berkley JA, Munywoki P, Ngama M, Kazungu S, Abwao J, Bett A, et al. Viral Etiology of Severe Pneumonia Among Kenyan Infants and Children. JAMA. 2010;303:2051-7.
  4. Howard TS, Hoffman LH, Stang PE, Simoes EA. Respiratory syncytial virus pneumonia in the hospital setting: length of stay, charges, and mortality. J Pediatr. 2000;137:227-32.
  5. Noyola DE, Zuviri-Gonzalez A, Castro-García JA, Ochoa-Zavala JR. Impact of respiratory syncytial virus on hospital admissions in children younger than 3 years of age. J Infect. 2007;54:180-4.
  6. World Health Organization. National burden of Disease studies: a practical guide. 2009 [en línea] [fecha de consulta: 23-X-2010]. Disponible en: http://www.who.int/healthinfo/nationalburdenofdiseasemanual.pdf

09/12/2010

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