June 2013. Volume 9. Number 2

Current evidence for the treatment of pediatric headaches is still unsatisfactory

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

El-Chammas K, Keyes J, Thompson N, Vijayakumar J, Becher D, Jackson JL. Pharmacologic Treatment of Pediatric Headaches: A Meta-analysis. JAMA Pediatr. 2013 Mar 1;167:250-8.
Reviewers: Cuello García CA1, Pérez Gaxiola G2.
1ITESM. Monterrey. Nuevo León. México.
2Hospital Pediátrico de Sinaloa. Culiacán. Sinaloa. México.
Correspondence: Carlos Alberto Cuello García. Email: carlos.cuello@gmail.com
Reception date: 19/04/2013
Acceptance date: 02/05/2013
Publication date: 16/05/2013

Abstract

Authors' conclusion: topiramate and trazodone have limited evidence supporting efficacy for episodic migraines.

Reviewers' commentary: trazodone and topiramate reduced the rate of monthly headache episodes; however, quality of the evidence was deemed moderate to low and the result might not be considered clinically significant, mainly because this reduction is equivalent to one less headache episode per month. None of these medications reduced at least 50% the frequency of headaches.

How to cite this article

Cuello García CA, Pérez Gaxiola G. La evidencia para el tratamiento de la cefalea y la migraña en niños y adolescentes sigue siendo limitada. Evid Pediatr. 2013;9:26.

AVC | Critically appraised articles

El-Chammas K, Keyes J, Thompson N, Vijayakumar J, Becher D, Jackson JL. Pharmacologic Treatment of Pediatric Headaches: A Meta-analysis. JAMA Pediatr. 2013 Mar 1;167:250-8.
Reviewers: Cuello García CA1, Pérez Gaxiola G2.
1ITESM. Monterrey. Nuevo León. México.
2Hospital Pediátrico de Sinaloa. Culiacán. Sinaloa. México.
Correspondence: Carlos Alberto Cuello García. Email: carlos.cuello@gmail.com
Reception date: 19/04/2013
Acceptance date: 02/05/2013
Publication date: 16/05/2013

How to cite this article

Cuello García CA, Pérez Gaxiola G. La evidencia para el tratamiento de la cefalea y la migraña en niños y adolescentes sigue siendo limitada. Evid Pediatr. 2013;9:26.

References

  1. Arruda MA, Guidetti V, Galli F, Albuquerque RC, Bigal ME. Primary headaches in childhood: a population-based study. Cephalalgia. 2010;30:1056-64.
  2. Victor S, Ryan SW. Drugs for preventing migraine headaches in children. Cochrane Database Syst Rev. 2003;4:CD002761.
  3. Bakola E, Tzoufi M, Damigos D, Mavreas V. Anticonvulsant drugs for pediatric migraine prevention: An evidence-based review. Eur J Pain. 2009;13:893-901.
  4. García Lara NR, Frías García ME. Tratamiento preventivo para la migraña en niños: cuándo y cómo. Evid Pediatr. 2010;6:3.

16/05/2013

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