December 2014. Volume 10. Number 4

Nebulized 3% hypertonic saline decreases hospital admissions in mild-moderate bronchiolitis

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Wu S, Baker C, Lang ME, Schrager SM, Liley FF, Papa C,et al. Nebulized hypertonic saline for bronchiolitis: a randomized clinical trial. JAMA Pediatr. 2014;168:657-63.
Reviewers: Gimeno Díaz de Atauri Á1, Aparicio Rodrigo M2.
1Servicio de Pediatría. Hospital Puerta de Hierro. Madrid. España.
2Centro de Salud Entreví­as. Área 1. Madrid. España.
Correspondence: Álvaro Gimeno Díaz de Atauri. Email: agimenodatauri@gmail.com
Reception date: 17/11/2014
Acceptance date: 24/11/2014
Publication date: 10/12/2014

Abstract

Authors' conclusions: hypertonic saline given to children with bronchiolitis in the emergency department decreases hospital admissions. We can detect no significant difference in Respiratory Distress Assessment Instrument score or length of stay between the patients receiving nebulized 3% hypertonic saline.

Reviewers' commentary: nebulized 3% hypertonic saline for mild-moderate bronchiolitis can decrease hospital admissions without adverse events. The effect on length of stay is still in doubt. In regard to this, the absence of effect found in this study could be due to methodological limitations.

How to cite this article

Gimeno Díaz de Atauri A, Aparicio Rodrigo M. El suero salino hipertónico al 3% reduce los ingresos por bronquiolitis leve-moderada. Evid Pediatr. 2014;10:60.

AVC | Critically appraised articles

Wu S, Baker C, Lang ME, Schrager SM, Liley FF, Papa C,et al. Nebulized hypertonic saline for bronchiolitis: a randomized clinical trial. JAMA Pediatr. 2014;168:657-63.
Reviewers: Gimeno Díaz de Atauri Á1, Aparicio Rodrigo M2.
1Servicio de Pediatría. Hospital Puerta de Hierro. Madrid. España.
2Centro de Salud Entreví­as. Área 1. Madrid. España.
Correspondence: Álvaro Gimeno Díaz de Atauri. Email: agimenodatauri@gmail.com
Reception date: 17/11/2014
Acceptance date: 24/11/2014
Publication date: 10/12/2014

How to cite this article

Gimeno Díaz de Atauri A, Aparicio Rodrigo M. El suero salino hipertónico al 3% reduce los ingresos por bronquiolitis leve-moderada. Evid Pediatr. 2014;10:60.

References

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  2. Mandelberg A, Amirav I. Hypertonic saline or high volume normal saline for viral bronchiolitis: mechanisms and rationale. Pediatr Pulmonol. 2010;45:36-40.
  3. Zhang L M-SR, Wainwright C, Klassen TP. Nebulised hypertonic saline solution for acute bronchiolitis in infants. Cochrane Database Syst Rev. 2013;7:CD006458.
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  5. Chen YJ, Lee WL, Wang CM, Chou HH. Nebulized Hypertonic Saline Treatment Reduces both Rate and Duration of Hospitalization for Acute Bronchiolitis in Infants: An Updated Meta-Analysis. Pediatr Neonatol. 2014;55:431-438.
  6. Teunissen J, Hochs AH, Vaessen-Verberne A, Boehmer AL, Smeets CC, Brackel H, et al. The effect of 3% and 6% hypertonic saline in viral bronchiolitis: a randomised controlled trial. Eur Respir J. 2014;44:913-21.
  7. Florin TA, Shaw KN, Kittick M, Yakscoe S, Zorc JJ. Nebulized hypertonic saline for bronchiolitis in the emergency department: a randomized clinical trial. JAMA Pediatr. 2014;168:664-70.
  8. Ralston SL, Lieberthal AS, Meissner HC, Alverson BK, Baley JE, Gadomski AM,et al. Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis. Pediatrics. 2014;134:e1474-502.

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Martínez Gimeno A. ¿Hemos de poner suero salino hipertónico a los lactantes con bronquiolitis en Urgencias Pediátricas? Evid Pediatr. 2014;10:59.
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