September 2015. Volume 11. Number 3

Risk of herpes zoster is greater after natural infection than after vaccination

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Su-Ying W, Wen-Liang L. Epidemiology of pediatric herpes zoster after varicella infection: a population-based study. Pediatrics. 2015;135:e565-71.
Reviewers: Díaz Cirujano AI1, Molina Arias M2.
1CS Rosa Luxemburgo. Madrid. España.
2Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Ana Isabel Díaz Cirujano. Email: anaisabel.diazc@gmail.com
Reception date: 17/07/2015
Acceptance date: 06/07/2015
Publication date: 15/07/2015

Abstract

Authors´ conclusions: the risk of developing herpes zoster is higher among those exposed to the disease than among the vaccinated. Before systematic vaccination, the incidence is higher and onset earlier when infection takes place between one and two years of age. During vaccination period, those with chickenpox with two or more years of age, have an increased risk of herpes zoster.

Reviewers´ commentary: although the study does not analyze costs, prevention of disease without increasing the incidence of herpes zoster would be in favor of routine vaccination against varicella in childhood. The impact after a longer period of monitoring implementation of universal vaccination should be analyzed.

How to cite this article

Díaz Cirujano AI, Molina Arias M. El riesgo de herpes zóster es mayor tras la infección natural que tras la vacunación. Evid Pediatr. 2015;11:43.

AVC | Critically appraised articles

Su-Ying W, Wen-Liang L. Epidemiology of pediatric herpes zoster after varicella infection: a population-based study. Pediatrics. 2015;135:e565-71.
Reviewers: Díaz Cirujano AI1, Molina Arias M2.
1CS Rosa Luxemburgo. Madrid. España.
2Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Ana Isabel Díaz Cirujano. Email: anaisabel.diazc@gmail.com
Reception date: 17/07/2015
Acceptance date: 06/07/2015
Publication date: 15/07/2015

How to cite this article

Díaz Cirujano AI, Molina Arias M. El riesgo de herpes zóster es mayor tras la infección natural que tras la vacunación. Evid Pediatr. 2015;11:43.

References

  1. Brisson M, Gay NJ Edmunds WJ, Andrews NJ. Exposure to varicela boosts inmunity to herpes zoster: implications for mass  vaccination against chickenpox. Vaccine. 2002;20:2500-7.
  2. Weinmann S, Chun C, Schmid DS, Roberts M, Vandermeer M, Riedlinger K, et al. Incidence and clinical characteristics of herpes zoster among children in the varicella vaccine era, 2005-2009. J Infect Dis. 2013;208:1859-68.
  3. Civen R, Chaves SS, Jumaan A, Wu H, Mascola L, Gargiullo P, et al. The incidence and clinical characteristics of herpes zoster among children and adolescents after implementation of varicella vaccination. Pediatr Infect Dis J. 2009;28:954-9.
  4. Wootton SH, Law B, Tan B, Mozel M, Scheifele DW, Halperin S, et al. The epidemiology of children hospitalized with herpes zoster in Canada: Immunization Monitoring Program, Active (IMPACT), 1991-2005. Pediatr Infect Dis J. 2008;27:112-8.
15/07/2015

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