March 2020. Volume 16. Number 1

Endocrine disrupting chemicals do not seem to be related with autism spectrum disorder or intellectual disability

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Hamra GB, Lyall K, Windham GC, Calafat AM, Sjödin A, Volk H, et al. Prenatal exposure to endocrine-disrupting chemicals in relation to autism spectrum disorder and intellectual disability. Epidemiology. 2019;30:418-26.

Reviewers: Rodríguez-Salinas Pérez E1, González Rodríguez P2.
1Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
2Pediatra. CS Barrio del Pilar. Madrid. España.
Correspondence: Enrique Rodríguez-Salinas Pérez. Email: erodriguez-salinas@pap.es
Reception date: 11/11/2019
Acceptance date: 20/12/2019
Publication date: 15/01/2020

Abstract

Authors’ conclusions: our mixtures analysis does not suggest an independent relationship of autism spectrum disorder or intellectual disability with any of the 25 chemicals examined together in this mixtures analysis.

Reviewers’ commentary: with this Bayesian probabilistic model, the authors clear up, at this moment, the uncertainty about the relationship between the main endocrine disruptors and autism spectrum disorders or intellectual disability, as the association shown in previous studies with “frequentist” analyzes is not demonstrated. It is an important result given the general concern about the effects of these universal pollutants.

How to cite this article

Rodríguez-Salinas E, González Rodríguez MP. Los disruptores endocrinos no parece que se asocien con el autismo o la discapacidad intelectual. Evid Pediatr. 2020;16:3.

AVC | Critically appraised articles

Hamra GB, Lyall K, Windham GC, Calafat AM, Sjödin A, Volk H, et al. Prenatal exposure to endocrine-disrupting chemicals in relation to autism spectrum disorder and intellectual disability. Epidemiology. 2019;30:418-26.

Reviewers: Rodríguez-Salinas Pérez E1, González Rodríguez P2.
1Pediatra. CS Colmenar Viejo Norte. Colmenar Viejo. Madrid. España.
2Pediatra. CS Barrio del Pilar. Madrid. España.
Correspondence: Enrique Rodríguez-Salinas Pérez. Email: erodriguez-salinas@pap.es
Reception date: 11/11/2019
Acceptance date: 20/12/2019
Publication date: 15/01/2020

How to cite this article

Rodríguez-Salinas E, González Rodríguez MP. Los disruptores endocrinos no parece que se asocien con el autismo o la discapacidad intelectual. Evid Pediatr. 2020;16:3.

15/01/2020

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