March 2010. Volume 6. Number 1

Varicella vaccine seems to decrease slightly the incidence of herpes zoster in young population although it could diminish its severity

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Civen R, Chaves SS, Jumaan A, Wu H, Mascola L, Gargiullo P, et al. The incidence and clinical characteristics of Herpes Zoster among children and adolescents after implementation of Varicella vaccination. Pediatr Infect Dis J. 2009;28:954-9
Reviewers: Chalco Orrego JP1, Rojas Galarza RA2.
1Pediatra independiente. Madrid. España.
2Unidad de Emergencia. Instituto Nacional de Salud del Niño. Lima. Perú.
Correspondence: Juan Pablo Chalco Orrego. Email: jpcho33@yahoo.com
Reception date: 03/03/2010
Acceptance date: 04/03/2010
Publication date: 25/03/2010

Abstract

Authors’ conclusions: varicella vaccine substantially decreases the risk of herpes zoster among vaccinated children and its widespread use will likely reduce overall herpes zoster burden in the United States. The increase in herpes zoster incidence among 10 to 19-year-olds could not be confidently explained and needs to be confirmed from other data sources.

Reviewers’ commentary: due to the lack of similar studies with longer follow-up it is too early to assume that varicella vaccination significantly reduces the incidence of herpes zoster in children, although there is a tendency to be less severe. The expanded indication for immunization against chickenpox is still valid while further research about epidemiological changes of herpes zoster is needed.

How to cite this article

Chalco Orrego JP. Bada Mancilla CA, Rojas Galarza RA. En población infantojuvenil la vacuna contra la varicela parece disminuir poco la incidencia de herpes zoster aunque sí podría disminuir su gravedad. Evid Pediatr. 2010;6:14.

AVC | Critically appraised articles

Civen R, Chaves SS, Jumaan A, Wu H, Mascola L, Gargiullo P, et al. The incidence and clinical characteristics of Herpes Zoster among children and adolescents after implementation of Varicella vaccination. Pediatr Infect Dis J. 2009;28:954-9
Reviewers: Chalco Orrego JP1, Rojas Galarza RA2.
1Pediatra independiente. Madrid. España.
2Unidad de Emergencia. Instituto Nacional de Salud del Niño. Lima. Perú.
Correspondence: Juan Pablo Chalco Orrego. Email: jpcho33@yahoo.com
Reception date: 03/03/2010
Acceptance date: 04/03/2010
Publication date: 25/03/2010

How to cite this article

Chalco Orrego JP. Bada Mancilla CA, Rojas Galarza RA. En población infantojuvenil la vacuna contra la varicela parece disminuir poco la incidencia de herpes zoster aunque sí podría disminuir su gravedad. Evid Pediatr. 2010;6:14.

References

  1. Edgar BL, Galanis E, Kay C, Skowronski D, Naus M, Patrick D. The burden of varicella and zoster in British Columbia 1994-2003: baseline assessment prior to universal vaccination. Can.Commun.Dis.Rep. 2007;33:1-15.
  2. Garcia Cenoz M, Castilla J, Montes Y, Moran J, Salaberri A, Elia F, et al.Incidencia de la varicela y el herpes zóster antes de la introducción dela vacunación sistemática infantil en Navarra, 2005-2006. An Sist.Sanit.Navar. 2008;31:71-80.
  3. Chaves S, Haber P, Walton K, Wise R, Izurieta H, Schmid D , et al. Safety of varicella vacine after licensure in the United States: experience from reports to the vaccine adverse event reporting system.,1995-2005. J.Infect.Dis. 2008;197:S170-7.
  4. Galea S, Sweet A, Beninger P, Steinberg S, LaRussa P, Gershon A, et al. The Safety Profile of Varicella Vaccine: A 10?Year Review. J.Infect.Dis. 2008;197:S165-9.
  5. Lin P, Yoon MK, Chiu CS. Herpes Zoster Keratouveitis and Inflammatory Ocular Hypertension 8 Years after Varicella Vaccination. Ocul.Immunol.Inflamm. 2009;17:33-5.
  6. Hambleton S, Steinberg S, LaRussa P, Shapiro E, Gershon A. Risk of Herpes Zoster in Adults Immunized with Varicella Vaccine. J.Infect.Dis. 2008;197:S196-9.
  7. Patel M, Gebremariam A, Davis M. Herpes Zoster?Related Hospitalizations and Expenditures Before and After Introduction of the Varicella Vaccine in the United States. Infect Control Hosp Epidemiol. 2008;29:1157-63.
25/03/2010

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