September 2010. Volume 6. Number 3

Ascorbic acid seems to facilitate the absorption of the iron content of the food commonly consumed by healthy children in the form of ferrous fumarate

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Balay KS, Hawthorne KM, Hicks PD, Griffin IJ, Chen Z, Westerman M, Abrams SA. Orange But Not Apple Juice Enhances Ferrous Fumarate Absorption in Small Children. JPGN. 2010;50:545–50.
Reviewers: Guarch Ibáñez B1, Buñuel Álvarez JC2.
1Hospital Universitario de Girona Dr. Josep Trueta. Girona. Girona. España.
2Àrea Bàsica de Salut Girona-4. Institut Català de la Salut. Girona. España.
Correspondence: Borja Guarch Ibáñez. Email: borjaguarch@hotmail.com
Reception date: 23/07/2010
Acceptance date: 26/07/2010
Publication date: 30/07/2010

Abstract

Authors’ conclusions: The administration of orange juice, which contains a modest dose of ascorbic acid, provides a significant increase in the absorption of ferrous fumarate in children without prior iron deficiency.

Reviewers’ commentary: The absorption of ferrous fumarate appears to be enhanced when it is administered together with ascorbic acid. It is not possible, however, to provide a direct comparison between ferrous fumarate and sulfate to know if the facilitating effect of the ascorbic acid absorption is similar for both forms of iron presentation. Studies in healthy children comparing the absorption of ferrous fumarate and ferrous sulfate administered with ascorbic acid are needed in order to determine which method of administration is the most effective and cost-effective.

How to cite this article

Guarch Ibáñez B, Buñuel Álvarez JC. En niños sanos, el ácido ascórbico parece facilitar la absorción del hierro contenido en los alimentos de consumo habitual en forma de fumarato ferroso. Evid Pediatr. 2010;6:53.

AVC | Critically appraised articles

Balay KS, Hawthorne KM, Hicks PD, Griffin IJ, Chen Z, Westerman M, Abrams SA. Orange But Not Apple Juice Enhances Ferrous Fumarate Absorption in Small Children. JPGN. 2010;50:545–50.
Reviewers: Guarch Ibáñez B1, Buñuel Álvarez JC2.
1Hospital Universitario de Girona Dr. Josep Trueta. Girona. Girona. España.
2Àrea Bàsica de Salut Girona-4. Institut Català de la Salut. Girona. España.
Correspondence: Borja Guarch Ibáñez. Email: borjaguarch@hotmail.com
Reception date: 23/07/2010
Acceptance date: 26/07/2010
Publication date: 30/07/2010

How to cite this article

Guarch Ibáñez B, Buñuel Álvarez JC. En niños sanos, el ácido ascórbico parece facilitar la absorción del hierro contenido en los alimentos de consumo habitual en forma de fumarato ferroso. Evid Pediatr. 2010;6:53.

References

  1. Davidsson L, Sarker SA, Jamil KA, Sultana S, Hurrell R. Regular consumption of a complementary food fortified with ascorbic acid and ferrous fumarate or ferric pyrophosphate is as useful as ferrous sulfate in maintaining hemoglobin concentrations .105 g/L in young Bangladeshi children. Am J Clin Nutr. 2009;89:1815–20.
  2. Tondeur MC, Schauer CS, Christofides AL, Asante KP, Newton S, Serfass RE, et al. Determination of iron absorption from intrinsically labelled microencapsulated ferrous fumarate (sprinkles) in infants with different iron and hematologic status by using a dual-stable-isotope method. Am J Clin Nutr. 2004;80:1436-44.
  3. Davidsson L, Kastenmayer P, Szajewska H, Hurrell RF, Barclay D. Iron bioavailability in infants from an infant cereal fortified with ferric pyrophosphate or ferrous fumarate. Am J Clin Nutr. 2000;71:1597–602.
  4. Morales J, Vargas F, Cassís L, Sánchez E, Villalpando S. Sensorial evaluation of nutritional supplements  (PROGRESA) enriched with 3 different forms of iron in  a rural Mexican community. J Food Sci. 2008;73:S1-5.
  5. Geltman PL, Hironaka LK, Mehta SD, Padilla P, Rodrigues P, Meyers AF,et al. Iron supplementation of low-income  infants: a randomized clinical trial of adherence with ferrous fumarate sprinkles versus ferrous sulfate drops. J Pediatr. 2009;154:738-43.
  6. PrevInfad. Prevención y detección de la ferropenia [actualizado: 14-X-2002][consultado: 23-VII-2010]. Disponible en: http://www.aepap.org/previnfad/ferropenia.htm#RECOMENDACIONES
30/07/2010

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