September 2014. Volume 10. Number 3

Can we predict which very preterm infants are likely to develop severe ventricular hemorrhage?

 
 
 
 
 
 
 
 
 
 
Rating: 0 (0 Votes)
Newsletter Free Subscription
Regularly recieve most recent articles by e-mail
Subscribe
Print
Add to library
Discuss this article

AVC | Critically appraised articles

Luque MJ, Tapia JL, Villarroel L, Marshall G, Musante G, Carlo W, et al. Neocosur Neonatal Network. A risk prediction model for severe intraventricular hemorrhage in very low birth weight infants and the effect of prophylactic indomethacin. J Perinatol. 2014;34:43-8.
Reviewers: Rivas Fernández MÁ1, Aizpurua Galdeano P2.
1Hospital General de Cataluña. Sant Cugat del Vallés. Barcelona. España.
2CS Amara Berri. San Sebastián. España.
Correspondence: Mª Ángeles Rivas Fernández. Email: mayrivas5@gmail.com
Reception date: 30/05/2014
Acceptance date: 14/07/2014
Publication date: 30/07/2014

Abstract

Authors' conclusions: a model for early severe intraventricular hemorrhage prediction was developed and tested in our population of very low birth weight infants. Prophylactic indomethacin was associated with a lower risk-adjusted incidence of severe intraventricular hemorrhage.

Reviewers' commentary: this study presents a simple five-variable model that, although with only moderate accuracy, can improve the selection of those very low birth weight preterms at high risk of developing severe ventricular hemorrhage. The association found between indomethacin prophylaxis and lower risk of major bleeding should be confirmed with studies designed to confirm the causal relationship and to evaluate the long-term neurologic outcomes of the treated children.

How to cite this article

Rivas Fernández MA, Aizpurua Galdeano P. ¿Es posible predecir qué neonatos muy prematuros presentarán una hemorragia intraventricular grave? Evid Pediatr. 2014;10:45.

AVC | Critically appraised articles

Luque MJ, Tapia JL, Villarroel L, Marshall G, Musante G, Carlo W, et al. Neocosur Neonatal Network. A risk prediction model for severe intraventricular hemorrhage in very low birth weight infants and the effect of prophylactic indomethacin. J Perinatol. 2014;34:43-8.
Reviewers: Rivas Fernández MÁ1, Aizpurua Galdeano P2.
1Hospital General de Cataluña. Sant Cugat del Vallés. Barcelona. España.
2CS Amara Berri. San Sebastián. España.
Correspondence: Mª Ángeles Rivas Fernández. Email: mayrivas5@gmail.com
Reception date: 30/05/2014
Acceptance date: 14/07/2014
Publication date: 30/07/2014

How to cite this article

Rivas Fernández MA, Aizpurua Galdeano P. ¿Es posible predecir qué neonatos muy prematuros presentarán una hemorragia intraventricular grave? Evid Pediatr. 2014;10:45.

References

  1. Bassan H. Intracranial hemorrhage in the preterm infant: understanding it, preventing it. Clin Perinatol. 2009;36:737-62.
  2. Fowlie PW, Davis PG, McGuire W. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. Cochrane Database of Syst Rev. 2010;7:CD000174.
  3. Roberts D, Dalziel S. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database of Syst Rev. 2013;3:CD004454.
  4. Heuchan AM, Evans N, Henderson Smart DJ, Simpson JM. Perinatal risk factors for major intraventricular haemorrhage in the Australian and New Zealand Neonatal Network, 1995-97. Arch Dis Child Fetal Neonatal. 2002;86:86-90.
  5. Vogtmann C, Koch R, Gmyrek D, Kaiser A, Friedrich A. Risk-adjusted intraventricular hemorrhage rates in very premature infants. Dtsch Arztebl Int. 2012;109:527-33.
30/07/2014

Linked Comment