March 2019. Volume 15. Number 1

Influenza in infants, is there evidence of the use of vitamin D3?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Zhou J, Du J, Huang L, Wang Y, Shi Y, Lin H. Preventive effects of vitamin D on seasonal influenza A in infants: a multicenter, randomized, open, controlled clinical trial. Pediatr Infect Dis J. 2018;37:749-54.

Reviewers: Ruiz-Canela Cáceres J1, García Vera C2.
1CS Virgen de África. Sevilla. España.
2CS José Ramón Muñoz Fernández. Zaragoza. España.
Correspondence: Juan Ruiz-Canela Cáceres. Email: jruizcanela@gmail.com
Reception date: 25/01/2019
Acceptance date: 12/02/2019
Publication date: 20/02/2019

Abstract

Authors’ conclusions: prophylaxis with high doses of Vitamin D (1200 IU / day) is adequate to prevent the flu epidemic, as demonstrated by the rapid reduction of symptoms, greater reduction of viral load and early recovery. In addition, its administration is probably safe in children.

Reviewers’ commentary: vitamin D is effective and safe in the prevention of influenza at a dose of 1200 units per day, but these data are unreliable, due to the methodological deficiencies of the study analyzed.

How to cite this article

Ruiz-Canela Cáceres J, García Vera C. Gripe en lactantes, ¿hay evidencia del uso de la vitamina D3? Evid Pediatr. 2019;15:8.

AVC | Critically appraised articles

Zhou J, Du J, Huang L, Wang Y, Shi Y, Lin H. Preventive effects of vitamin D on seasonal influenza A in infants: a multicenter, randomized, open, controlled clinical trial. Pediatr Infect Dis J. 2018;37:749-54.

Reviewers: Ruiz-Canela Cáceres J1, García Vera C2.
1CS Virgen de África. Sevilla. España.
2CS José Ramón Muñoz Fernández. Zaragoza. España.
Correspondence: Juan Ruiz-Canela Cáceres. Email: jruizcanela@gmail.com
Reception date: 25/01/2019
Acceptance date: 12/02/2019
Publication date: 20/02/2019

How to cite this article

Ruiz-Canela Cáceres J, García Vera C. Gripe en lactantes, ¿hay evidencia del uso de la vitamina D3? Evid Pediatr. 2019;15:8.

20/02/2019

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