June 2011. Volume 7. Number 2

The evidence linking diabetes type 1 infection with enteroviruses is currently insufficient

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Yeung WC, Rawlinson WD, Craig ME. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ. 2011;342:d35.
Reviewers: Guarch Ibáñez B1, Llerena Santa Cruz E2, Buñuel Álvarez JC3.
1Hospital Universitario Dr. Josep Trueta. Girona. España.
2Hospital Universitario Dr. Josep Trueta. Girona. España.
3Àrea Bàsica de Salut Girona-4. Institut Català de la Salut. Girona. España.
Correspondence: Borja Guarch Ibáñez. Email: borjaguarch@hotmail.com
Reception date: 14/05/2011
Acceptance date: 17/05/2011
Publication date: 01/06/2011

Abstract

Authors’ conclusions: there is an association between enterovirus infection, detected by molecular methods, and autoimmunity/type 1 diabetes.

Reviewers’ commentary: there a ppears to be an association bet ween enterovirus detectionand the presence of prediabetes/type 1 diabetes. This association can not be interpreted as causal due to design limitations of the individual studies. In order to establish the existence of causality it is necessary to conduct a prospective population-based cohort study.

How to cite this article

Guarch Ibáñez B, Llerena Santa Cruz E, Buñuel Álvarez JC. Las pruebas que relacionan la diabetes tipo 1 con infección previa por enterovirus son actualmente insuficientes. Evid Pediatr. 2011;7:29.

AVC | Critically appraised articles

Yeung WC, Rawlinson WD, Craig ME. Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies. BMJ. 2011;342:d35.
Reviewers: Guarch Ibáñez B1, Llerena Santa Cruz E2, Buñuel Álvarez JC3.
1Hospital Universitario Dr. Josep Trueta. Girona. España.
2Hospital Universitario Dr. Josep Trueta. Girona. España.
3Àrea Bàsica de Salut Girona-4. Institut Català de la Salut. Girona. España.
Correspondence: Borja Guarch Ibáñez. Email: borjaguarch@hotmail.com
Reception date: 14/05/2011
Acceptance date: 17/05/2011
Publication date: 01/06/2011

How to cite this article

Guarch Ibáñez B, Llerena Santa Cruz E, Buñuel Álvarez JC. Las pruebas que relacionan la diabetes tipo 1 con infección previa por enterovirus son actualmente insuficientes. Evid Pediatr. 2011;7:29.

References

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  5. Oikarinen S, Martiskainen M, Tauriainen S, Huhtala H, Ilonen J, Veijola R et al. Enterovirus RNA in blood is linked to the development of type 1 diabetes. Diabetes. 2011:276-9.
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01/06/2011

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