June 2014. Volume 10. Number 2

Does Lactobacillus reuteri have a role in the treatment of infantile colic?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Sung V, Hiscock H, Tang ML, Mensah FK, Nation ML, Satzke C, et al. Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial. BMJ. 2014;348:g2107.
Reviewers: Aparicio Rodrigo M1, González de Dios J2.
1Centro de Salud Entreví­as. Área 1. Madrid. España.
2Departamento de Pediatría. Hospital General Universitario de Alicante. España.
Correspondence: María Aparicio Rodrigo. Email: maparicio@salud.madrid.org
Reception date: 29/03/2014
Acceptance date: 05/05/2014
Publication date: 21/05/2014

Abstract

Authors' conclusions: Lactobacillus reuteri DSM 17938 did not benefit a community sample of breastfed infants and formula fed infants with colic. These findings differ from previous smaller trials of selected populations and do not support a general recommendation for the use of probiotics to treat colic in infants.

Reviewers' commentary: the results of this study question the efficacy of Lactobacillus reuteri in the treatment of infants with colic. For now and until more conclusive data, it seems reasonable not to include probiotics in our recommendations for the management of infantile colic.

How to cite this article

Aparicio Rodrigo M, González de Dios J. ¿Es útil el probiótico Lactobacillus reuteri en el cólico infantil? Evid Pediatr. 2014;10:29.

AVC | Critically appraised articles

Sung V, Hiscock H, Tang ML, Mensah FK, Nation ML, Satzke C, et al. Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial. BMJ. 2014;348:g2107.
Reviewers: Aparicio Rodrigo M1, González de Dios J2.
1Centro de Salud Entreví­as. Área 1. Madrid. España.
2Departamento de Pediatría. Hospital General Universitario de Alicante. España.
Correspondence: María Aparicio Rodrigo. Email: maparicio@salud.madrid.org
Reception date: 29/03/2014
Acceptance date: 05/05/2014
Publication date: 21/05/2014

How to cite this article

Aparicio Rodrigo M, González de Dios J. ¿Es útil el probiótico Lactobacillus reuteri en el cólico infantil? Evid Pediatr. 2014;10:29.

References

  1. National Institute for Health and Care Excellence guidelines [internet]. Colic infantiles. Clinical Knowlledge summaries. Last revised in August 2012. [en línea] [consultado el 29/4/2014]. Disponible en http://cks.nice.org.uk/colic-infantile#!management
  2. Sung V, Collett S, de Gooyer T, Hiscock H, Tang M, Wake M. Probiotics to prevent or treat excessive infant crying: systematic review and meta-analysis. JAMA Pediatr. 2013;167:1150-7.
  3. Szajewska H, Gyrczuk E, Horvath A. Lactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind, placebo-controlled trial. J Pediatr. 2013;162:257-62.
  4. Savino F, Pelle E, Palumeri E, Oggero R, Miniero R. Lactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized study. Pediatrics. 2007;119:e124-30.
  5. Savino F, Cordisco L, Tarasco V, Palumeri E, Calabrese R, Oggero R, et al. Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial. Pediatrics. 2010;126:e526-33.
21/05/2014

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