March 2015. Volume 11. Number 1

Around 3% of children who developed tuberculosis had multidrug-resistant disease

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Jenkins HE, Tolman AW, Yuen CM, Parr JB, Keshavjee S, Pérez-Vélez CM, et al. Incidence of multidrug-resistant tuberculosis disease in children: systematic review and global estimates. Lancet. 2014;383:1572-9.

Reviewers: García Vera C1, Ruiz-Canela Cáceres J2.
1CS Sagasta-Ruiseñores. Zaragoza. España.
2CS Virgen de África. Sevilla. España.
Correspondence: César García Vera. Email: cgarciavera@gmail.com
Reception date: 10/09/2014
Acceptance date: 31/10/2014
Publication date: 15/01/2015

Abstract

Authors´ conclusions: systematic review shows that many cases of tuberculosis and multidrug-resistant tuberculosis are not detected properly in children. The estimates could be much closer to reality if the epidemiological data would be more accurate and better availability of new diagnostic procedures.

Reviewers´ commentary: this systematic review on the incidence of multidrug-resistant tuberculosis in children reveals that this would be the case for a 3% of the newly diagnosed tuberculosis in children, although there is still a need for better epidemiological data and more accurate diagnostic tools worldwide.

How to cite this article

García Vera C, Ruiz-Canela Cáceres J. La incidencia de tuberculosis multirresistente en la infancia podría aproximarse al 3%. Evid Pediatr. 2015;11:5.

AVC | Critically appraised articles

Jenkins HE, Tolman AW, Yuen CM, Parr JB, Keshavjee S, Pérez-Vélez CM, et al. Incidence of multidrug-resistant tuberculosis disease in children: systematic review and global estimates. Lancet. 2014;383:1572-9.

Reviewers: García Vera C1, Ruiz-Canela Cáceres J2.
1CS Sagasta-Ruiseñores. Zaragoza. España.
2CS Virgen de África. Sevilla. España.
Correspondence: César García Vera. Email: cgarciavera@gmail.com
Reception date: 10/09/2014
Acceptance date: 31/10/2014
Publication date: 15/01/2015

How to cite this article

García Vera C, Ruiz-Canela Cáceres J. La incidencia de tuberculosis multirresistente en la infancia podría aproximarse al 3%. Evid Pediatr. 2015;11:5.

References

  1. World Health Organization. Global Tuberculosis Control: WHO Report 2011. Ginebra: World Health Organization; 2011.
  2. World Health Organization. Multidrug and extensively drug-resistant TB (M/XDR-TB): 2010 global report on surveillance and response. Ginebra: World Health Organization; 2010.
  3. Marais BJ. Quantifying the tuberculosis disease burden in children. Lancet. 2014;383:1530-1.
  4. Zignol M, Hosseini MS, Wright A, Weezenbeek CL, Nunn P, Watt CJ, et al. Global incidence of multidrug-resistant tuberculosis. J Infect Dis. 2006;194:479-85.
  5. Seddon JA, Hesseling AC, Marais BJ, McIlleron H, Peloquin CA, Donald PR, et al. Paediatric use of second-line anti-tuberculosis agents: a review. Tuberculosis (Edinb). 2012;92:9-17.
15/01/2015

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