March 2019. Volume 15. Number 1

PCR to Enterovirus in fever without source in children under 2 years. Keep me in mind!

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Lafolie J, Labbé A, L’Honneur AL, Madhi F, Pereira B, Decobert M, et al. Assessment of blood enterovirus PCR testing in paediatric populations with fever without source, sepsis-like disease, or suspected meningitis: a prospective, multicentre, observational cohort study. Lancet Infect Dis. 2018;18:1385-96.

Reviewers: Flores Villar S1, Pérez-Moneo Agapito B2.
1Área de Hospitalización Pediátrica. Hospital Universitario Fundación Mútua Terrassa. Barcelona. España.
2Hospital Universitario Infanta Leonor. Madrid. España.
Correspondence: Sergio Flores Villar. Email: sflores@mutuaterrassa.es
Reception date: 19/03/2019
Acceptance date: 22/03/2019
Publication date: 27/03/2019

Abstract

Conclusions of the authors of the study: enterovirus PCR should be part of the clinical practice guidelines for children 2 years old and younger. This test could reduce the length of hospital stay and reduce exposure to antibiotics for low-risk patients admitted from the emergency room with febrile illness.

Reviewers' commentary: detection of enteroviruses in blood can lead to reduced admissions and to a reduction in the use of antibiotic therapy in newborns and infants who come to the emergency room with fever without source and / or with sepsis-like disease, during the seasonal periods of high prevalence of the virus. There may be a marginal benefit in children with meningitis symptoms.

How to cite this article

Flores Villar S, Pérez-Moneo Agapito B. PCR a enterovirus en la fiebre sin foco. Pensad en mí. Evid Pediatr. 2019;15:11.

AVC | Critically appraised articles

Lafolie J, Labbé A, L’Honneur AL, Madhi F, Pereira B, Decobert M, et al. Assessment of blood enterovirus PCR testing in paediatric populations with fever without source, sepsis-like disease, or suspected meningitis: a prospective, multicentre, observational cohort study. Lancet Infect Dis. 2018;18:1385-96.

Reviewers: Flores Villar S1, Pérez-Moneo Agapito B2.
1Área de Hospitalización Pediátrica. Hospital Universitario Fundación Mútua Terrassa. Barcelona. España.
2Hospital Universitario Infanta Leonor. Madrid. España.
Correspondence: Sergio Flores Villar. Email: sflores@mutuaterrassa.es
Reception date: 19/03/2019
Acceptance date: 22/03/2019
Publication date: 27/03/2019

How to cite this article

Flores Villar S, Pérez-Moneo Agapito B. PCR a enterovirus en la fiebre sin foco. Pensad en mí. Evid Pediatr. 2019;15:11.

27/03/2019

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