March 2021. Volume 17. Number 1

Pfizer-BioNTech, the first ARNm vaccine against COVID-19, seems safe and effective

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med. 2020;383:2603-15.

Reviewers: Esparza Olcina MJ1, Juanes de Toledo B2.
1Pediatra. Madrid. España.
2EAP Collado Villalba pueblo. Collado Villalba. Madrid. España.
Correspondence: María Jesús Esparza Olcina. Email: mjesparza8@gmail.com
Reception date: 07/03/2021
Acceptance date: 17/03/2021
Publication date: 31/03/2021

Abstract

Conclusions of the authors of the study: the BNT-162b2 vaccine, administered in two doses 21 days apart, is safe and provides 95% efficacy against COVID-19.

Reviewers’ comment: preliminary data suggest that the BNT-162b2 vaccine is effective and safe in preventing symptomatic COVID-19 disease in adults over 16 years of age. Although the duration of protection is unknown, and it has not yet been studied in children under 16 years of age, immunosuppressed or pregnant individuals. We do not know the infrequent or late adverse effects.

How to cite this article

Esparza Olcina MJ, Juanes de Toledo B. Pfizer-BioNTech, la primera vacuna ARNm contra la COVID-19, parece segura y eficaz. Evid Pediatr. 2021;17:6.

AVC | Critically appraised articles

Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med. 2020;383:2603-15.

Reviewers: Esparza Olcina MJ1, Juanes de Toledo B2.
1Pediatra. Madrid. España.
2EAP Collado Villalba pueblo. Collado Villalba. Madrid. España.
Correspondence: María Jesús Esparza Olcina. Email: mjesparza8@gmail.com
Reception date: 07/03/2021
Acceptance date: 17/03/2021
Publication date: 31/03/2021

How to cite this article

Esparza Olcina MJ, Juanes de Toledo B. Pfizer-BioNTech, la primera vacuna ARNm contra la COVID-19, parece segura y eficaz. Evid Pediatr. 2021;17:6.

31/03/2021

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