June 2022. Volume 18. Number 2

BNT162b2 vaccine appears to be highly effective against SARS-CoV2 infection and disease in adolescents

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

June Choe Y, Yi S, Hwang I, Kim J, Park YJ, Cho E, et al. Safety and effectiveness of BNT162b2 mRNA Covid-19 vaccine in adolescents. Vaccine. 2022;40:691-4.
Reviewers: Fraile Astorga G1, Ochoa Sangrador C2.
1Pediatra. CS Portillo. Valladolid. España.
2Servicio de Pediatría. Hospital Virgen de la Concha. Zamora. España.
Correspondence: Garazi Fraile Astorga. Email: garazifraile@hotmail.com
Reception date: 04/05/2022
Acceptance date: 18/05/2022
Publication date: 01/06/2022

Abstract

Authors´ conclusions: in this retrospective cohort study, BNT162b2 vaccination was safe and was associated with a significantly lower risk of SARS-CoV-2 infection, suggesting that vaccination in adolescent may reduce the burden of COVID-19.

Reviewers´ commentary: this study support the safety profile and effectiveness of BNT162b2 vaccine, with impact on the reduction of COVID-19 disease, in line with strategy for the control of the pandemic. The mutation capacity of the virus must be taken into consideration, different variants could have different response to the vaccine.

Key words: adolescent; COVID-19; vaccine

How to cite this article

Fraile Astorga G, Ochoa Sangrador C. La vacuna BNT162b2 parece tener una alta efectividad frente a la infección y enfermedad por SARS-CoV-2 en adolescentes. Evid Pediatr. 2022;18:18.

AVC | Critically appraised articles

June Choe Y, Yi S, Hwang I, Kim J, Park YJ, Cho E, et al. Safety and effectiveness of BNT162b2 mRNA Covid-19 vaccine in adolescents. Vaccine. 2022;40:691-4.
Reviewers: Fraile Astorga G1, Ochoa Sangrador C2.
1Pediatra. CS Portillo. Valladolid. España.
2Servicio de Pediatría. Hospital Virgen de la Concha. Zamora. España.
Correspondence: Garazi Fraile Astorga. Email: garazifraile@hotmail.com
Key words: adolescent; COVID-19; vaccine
Reception date: 04/05/2022
Acceptance date: 18/05/2022
Publication date: 01/06/2022

How to cite this article

Fraile Astorga G, Ochoa Sangrador C. La vacuna BNT162b2 parece tener una alta efectividad frente a la infección y enfermedad por SARS-CoV-2 en adolescentes. Evid Pediatr. 2022;18:18.

01/06/2022

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