June 2022. Volume 18. Number 2

Peanut allergy in children: probable window of opportunity for desensitization

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Jones SM, Kim EH, Nadeau KC, Nowak-Wegrzyn A, Wood RA, Sampson HA, et al. Efficacy and safety of oral immunotherapy in children aged 1–3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study. Lancet. 2022; 399:359-71.

Reviewers: Flores Villar S1, Molina Arias M2.
1Pediatra. Área de Hospitalización Pediátrica. Hospital Universitario MútuaTerrassa. Barcelona. España.
2Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Sergio Flores Villar. Email: sflores@mutuaterrassa.es
Reception date: 10/06/2022
Acceptance date: 20/06/2022
Publication date: 22/06/2022

Abstract

Authors´ conclusions: children under 4 years of age allergic to peanuts who received oral allergen immunotherapy presented greater desensitization and remission to it, correlating with immunological biomarkers. Therefore, there seems to be a window of opportunity to become desensitized to peanuts in this age group.

Reviewers´ commentary: immunotherapy has been shown to be effective in achieving desensitization and remission in peanut-allergic children between 1 and 4 years of age. This effect was more evident in the younger age group and with lower levels of immunological markers.

How to cite this article

Flores Villar S, Molina Arias M. Alergia al cacahuete en niños: probable ventana de oportunidad para la desensibilización. Evid Pediatr. 2022;18:19.

AVC | Critically appraised articles

Jones SM, Kim EH, Nadeau KC, Nowak-Wegrzyn A, Wood RA, Sampson HA, et al. Efficacy and safety of oral immunotherapy in children aged 1–3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study. Lancet. 2022; 399:359-71.

Reviewers: Flores Villar S1, Molina Arias M2.
1Pediatra. Área de Hospitalización Pediátrica. Hospital Universitario MútuaTerrassa. Barcelona. España.
2Servicio de Gastroenterología. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Sergio Flores Villar. Email: sflores@mutuaterrassa.es
Reception date: 10/06/2022
Acceptance date: 20/06/2022
Publication date: 22/06/2022

How to cite this article

Flores Villar S, Molina Arias M. Alergia al cacahuete en niños: probable ventana de oportunidad para la desensibilización. Evid Pediatr. 2022;18:19.

22/06/2022

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