December 2022. Volume 18. Number 4

Dupilumab can serve as adjunctive therapy in children with moderate-severe poorly controlled asthma

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Bacharier LB, Maspero JF, Katelaris CH, Fiocchi AG, Gagnon R, De Mir I, et al. Dupilumab in Children with Uncontrolled Moderate-to-Severe Asthma. N Engl J Med.2021;385:2230-40.

Reviewers: Sánchez Mateo A1, Albi Rodríguez MS2.
1Pediatra. CS Josep Masdevall. Figueres. Gerona. España.
2Servicio de Neumología y Alergia Infantil. Hospital Universitario 12 de Octubre. Madrid. España.
Correspondence: Aina Sánchez Mateo . Email: ainasanchez280@gmail.com
Reception date: 27/09/2022
Acceptance date: 05/10/2022
Publication date: 13/10/2022

Abstract

Authors´ conclusions: among children with uncontrolled moderate-to-severe asthma, those who received add-on dupilumab had fewer asthma exacerbations and better lung function and asthma control than those who received placebo

Reviewers´ commentary: in children with moderate-severe asthma and a type 2 eosinophilic inflammatory profile, add-on dupilumab is an effective treatment, subject to cost and administration conditions.

How to cite this article

Sánchez Mateo A, Albi Rodríguez MS. El dupilumab puede servir como terapia coadyuvante en niños con asma moderada-grave mal controlada. Evid Pediatr. 2022;18:35.

AVC | Critically appraised articles

Bacharier LB, Maspero JF, Katelaris CH, Fiocchi AG, Gagnon R, De Mir I, et al. Dupilumab in Children with Uncontrolled Moderate-to-Severe Asthma. N Engl J Med.2021;385:2230-40.

Reviewers: Sánchez Mateo A1, Albi Rodríguez MS2.
1Pediatra. CS Josep Masdevall. Figueres. Gerona. España.
2Servicio de Neumología y Alergia Infantil. Hospital Universitario 12 de Octubre. Madrid. España.
Correspondence: Aina Sánchez Mateo . Email: ainasanchez280@gmail.com
Reception date: 27/09/2022
Acceptance date: 05/10/2022
Publication date: 13/10/2022

How to cite this article

Sánchez Mateo A, Albi Rodríguez MS. El dupilumab puede servir como terapia coadyuvante en niños con asma moderada-grave mal controlada. Evid Pediatr. 2022;18:35.

13/10/2022

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