December 2025. Volume 21. Number 4

Is intestinal ultrasound useful for the diagnosis of pediatric inflammatory bowel disease?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Khan HH, Munden MM, Spence LH, Jones RH, Whatley J, Suppa C. Intestinal ultrasound at diagnosis of pediatric inflammatory bowel disease compared to endoscopy. J Pediatr Gastroenterol Nutr. 2025;80:440-5.

Reviewers: Llerena Santa Cruz E1, Pérez Solís D2.
1Pediatra. CAP La Torrassa. L´Hospitalet de Llobregat. Barcelona. Hospital Joan XXIII. Tarragona. España.
2Servicio de Pediatría. Hospital Universitario de Cabueñes. Gijón. Asturias. España.
Correspondence: Enrique Llerena Santa Cruz. Email: kikellerena@gmail.com
Reception date: 06/11/2025
Acceptance date: 14/11/2025
Publication date: 26/11/2025

Abstract

Authors´ conclusions: intestinal ultrasound can be considered a screening tool for pediatric inflammatory bowel disease (IBD). It has reasonable sensitivity, specificity, positive predictive value, and negative predictive value, particularly for moderate-to-severe disease. The severity noted on IU correlated with fecal calprotectin and endoscopic disease activity but did not correlate with clinical disease activity.

Reviewers´ commentary: this study shows a limited number needed to diagnose; it was conducted at a single center and with a small sample size. Results could possibly be improved if a different cut-off for intestinal wall thickness were used, as mentioned in other studies. Given its high cost-effectiveness, it is a useful tool in the management of IBD, but its parameters and scales in pediatrics remain to be defined.

How to cite this article

Llerena Santa Cruz E, Pérez Solís D. ¿Es útil la ecografía intestinal para el diagnóstico de la enfermedad inflamatoria intestinal pediátrica? Evid Pediatr. 2025;21:47.

AVC | Critically appraised articles

Khan HH, Munden MM, Spence LH, Jones RH, Whatley J, Suppa C. Intestinal ultrasound at diagnosis of pediatric inflammatory bowel disease compared to endoscopy. J Pediatr Gastroenterol Nutr. 2025;80:440-5.

Reviewers: Llerena Santa Cruz E1, Pérez Solís D2.
1Pediatra. CAP La Torrassa. L´Hospitalet de Llobregat. Barcelona. Hospital Joan XXIII. Tarragona. España.
2Servicio de Pediatría. Hospital Universitario de Cabueñes. Gijón. Asturias. España.
Correspondence: Enrique Llerena Santa Cruz. Email: kikellerena@gmail.com
Reception date: 06/11/2025
Acceptance date: 14/11/2025
Publication date: 26/11/2025

How to cite this article

Llerena Santa Cruz E, Pérez Solís D. ¿Es útil la ecografía intestinal para el diagnóstico de la enfermedad inflamatoria intestinal pediátrica? Evid Pediatr. 2025;21:47.

26/11/2025

Linked Comment

Methodological note