June 2026. Volume 22. Number 2

Budesonide and pulmonary surfactant, a new agent in the prevention of bronchopulmonary dysplasia?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Wang K, Dan C, Gao S, Guang Y, Ju R. Airway Administration of Budesonide Combined With Pulmonary Surfactant to Prevent Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review and Meta‐Analysis. Pediatric Pulmonology. 2025;60:e71308.

Reviewers: Gámez Belmonte A1, Aparicio Rodrigo M2.
1Servicio de Pediatría. Hospital de Antequera. Antequera. Málaga. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Ana Gámez Belmonte. Email: ana_gamez_@hotmail.com
Reception date: 15/04/2026
Acceptance date: 20/04/2026
Publication date: 29/04/2026

Abstract

Authors´ conclusions: compared to the use of pulmonary surfactant alone, the combination of budesonide and pulmonary surfactant may prevent bronchopulmonary dysplasia in preterm infants, and does not increase the occurrence of related complications

Reviewers´ commentary: administration of budesonide alongside pulmonary surfactant seems to decrease the risk of bronchopulmonary dysplasia, but the magnitude of this effect can be uncertain and there is a lack of information, specially about long-term effects, to be able to recommend it systematically.

How to cite this article

Gámez Belmonte A, Aparicio Rodrigo M. Budesonida junto a surfactante pulmonar, ¿un nuevo agente en la prevención de la displasia broncopulmonar? Evid Pediatr. 2026;22:14.

AVC | Critically appraised articles

Wang K, Dan C, Gao S, Guang Y, Ju R. Airway Administration of Budesonide Combined With Pulmonary Surfactant to Prevent Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review and Meta‐Analysis. Pediatric Pulmonology. 2025;60:e71308.

Reviewers: Gámez Belmonte A1, Aparicio Rodrigo M2.
1Servicio de Pediatría. Hospital de Antequera. Antequera. Málaga. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Ana Gámez Belmonte. Email: ana_gamez_@hotmail.com
Reception date: 15/04/2026
Acceptance date: 20/04/2026
Publication date: 29/04/2026

How to cite this article

Gámez Belmonte A, Aparicio Rodrigo M. Budesonida junto a surfactante pulmonar, ¿un nuevo agente en la prevención de la displasia broncopulmonar? Evid Pediatr. 2026;22:14.

29/04/2026

Linked Comment

Methodological note