The risk of anaphylaxis following quadrivalent human papillomavirus vaccination is low" />

December 2008. Volume 4. Number 4

The risk of anaphylaxis following quadrivalent human papillomavirus vaccination is low

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Brotherton JM, Gold MS, Kemp AS, McIntyre PB, Burgess MA, Campbell-Lloyd S; New South Wales Health HPV Adverse Events Panel. Anaphylaxis following quadrivalent human papillomavirus vaccination. CMAJ. 2008;179:525-33
Reviewers: Cuervo Valdés JJ1, Carreazo Pariasca NY2.
1CS Ciudad Jardín. Badajoz. España.
2Hospital de Emergencias Pediátricas. Lima. Perú.
Correspondence: Jaime Javier Cuervo Valdés. Email: jaimejcv@gmail.com
Reception date: /11/2008
Acceptance date: 10/11/2008
Publication date: 01/12/2008

Abstract

Authors' conclusions: based on the number of confirmed cases, the estimated rate of anaphylaxis following quadrivalent human papillomavirus vaccine was significantly higher than the identified in other comparable vaccines. However, overall rates were very low and all cases were managed appropriately with no serious sequelae.

Reviewers' comantary: even taking into account the methodological problems of this study, the quadrivalent human papillomavirus vaccine seems to be safe to be used in massive vaccine campaigns. The anaphylaxis rate should be confirmed in other populations.

How to cite this article

Cuervo Valdés JJ, Carreazo Pariasca NY. El riesgo de reacción anafiláctica tras la vacunación frente al virus del papiloma humano es bajo. Evid Pediatr. 2008;4:86.

AVC | Critically appraised articles

Brotherton JM, Gold MS, Kemp AS, McIntyre PB, Burgess MA, Campbell-Lloyd S; New South Wales Health HPV Adverse Events Panel. Anaphylaxis following quadrivalent human papillomavirus vaccination. CMAJ. 2008;179:525-33
Reviewers: Cuervo Valdés JJ1, Carreazo Pariasca NY2.
1CS Ciudad Jardín. Badajoz. España.
2Hospital de Emergencias Pediátricas. Lima. Perú.
Correspondence: Jaime Javier Cuervo Valdés. Email: jaimejcv@gmail.com
Reception date: /11/2008
Acceptance date: 10/11/2008
Publication date: 01/12/2008

How to cite this article

Cuervo Valdés JJ, Carreazo Pariasca NY. El riesgo de reacción anafiláctica tras la vacunación frente al virus del papiloma humano es bajo. Evid Pediatr. 2008;4:86.

References

  1. Centers for Disease Control and Prevention. Gardasil Vaccine Reports to VAERS. Atlanta (GA); The Center; 2008. [en línea][fecha de consulta: 31-X-2008]. Disponible en: http://www.cdc.gov/vaccinesafety/vaers/gardasil.htm
  2. MacDonald N, Stanbrook MB, Hébert PC. Human papillomavirus vaccine risk and reality. CMAJ. 2008;179:503-5.
  3. World Health Organization. Adverse events following immunization: causality assessment. Geneva: The Organization; 2008. [en línea][fecha de consulta: 31-X-2008]. Disponible en: http://www.who.int/vaccines-documents/DocsPDF05/815.pdf
01/12/2008

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