June 2009. Volume 5. Number 2

A vaccine against cyomegalovirus infection could decrease the incidence of maternal infection in seronegative women of childbearing age

 
 
 
 
 
 
 
 
 
 
Rating: 0 (0 Votes)
Newsletter Free Subscription
Regularly recieve most recent articles by e-mail
Subscribe
Print
Add to library
Discuss this article

AVC | Critically appraised articles

Pass RF, Zhang CH, Evans A, Simpson T, Andrews W, Huang M et al. Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med 2009;360:1191-9
Reviewer: Orejón de Luna G1.
1CS General Ricardos. Madrid. España.
Correspondence: Gloria Orejón de Luna. Email: gloriaglo04@hotmail.com
Reception date: 30/04/2009
Acceptance date: 05/05/2009
Publication date: 01/06/2009

Abstract

Authors´ conclusions: cytomegalovirus (CMV) glycoprotein B vaccine has te potential to decrease incident cases of maternal CMV infection.

Reviewers´ commentary: Implications for practice: CMV glycoprotein B vaccine vaccine seems to be a efficacious vaccine against CMV infection in CMV seronegative women. Implication for investigation: more studies are needed to confirm the efficacy and safety of the cytomegalovirus vaccines in order to include it in immunization of women, before the first pregnancy.

How to cite this article

Orejón de Luna G. Una vacuna contra citomegalovirus podría disminuir la incidencia de infección materna en mujeres seronegativas en edad fértil. Evid Pediatr 2009;5:42

AVC | Critically appraised articles

Pass RF, Zhang CH, Evans A, Simpson T, Andrews W, Huang M et al. Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med 2009;360:1191-9
Reviewer: Orejón de Luna G1.
1CS General Ricardos. Madrid. España.
Correspondence: Gloria Orejón de Luna. Email: gloriaglo04@hotmail.com
Reception date: 30/04/2009
Acceptance date: 05/05/2009
Publication date: 01/06/2009

How to cite this article

Orejón de Luna G. Una vacuna contra citomegalovirus podría disminuir la incidencia de infección materna en mujeres seronegativas en edad fértil. Evid Pediatr 2009;5:42

References

  1. Fowler KB, Stagno S, Pass RF. Maternal immnunity an prevention of congenital cytomegalovirus infection. JAMA. 2003;289:1008-11.
  2. Foulon I, Naessens A, Foulon W, Castells A, Gordts F. Hearin loss in Children with congenital cytomegalovirus infection in relation to the maternal trimester in wich the maternal primary infection occurred. Pediatrics. 2008;122:e1123-7.
  3. Pass RF, Duliegè AM, Boppana S, Sekulovich R, Percell S, Britt W et al. A subuniti cytomegalovirus vaccine bassed on recombinant envelope glycoprotein B and a nuew adjuvant. J Infect Dis. 1999;180:970-5.
  4. Mitchell DK, HOlems SJ, Burke RL, Duliege AM, Adler SP. Immunogenicity of a recombinant human cytomegaglorirus gB vaccine in seronegative toddlers. Pediatr Infect Dis J. 2002 21:133-8.
  5. Dekker CL, Harbin AM. On step closer to a CMV vaccine. N Engl J. Med. 2009;260:1250-2.
01/06/2009

Linked Comment