Authors´ conclusions: in the studied population of 2-7-year old children with autism, the use of oxygen hyperbaric to 1.3 atm and 24 % of oxygen is sure and can improve certain behaviors as overall functioning, receptive language, social interaction, eye contact, and sensory/cognitive awareness compared to children who received slightly pressurized room air. Of the obtained results and of other previous studies it seems that the hyperbaric treatment is a promising therapy in children with autism.
Reviewers´ commentary: different results were obtained according to whom were the observers, parents or physicians, so the hyperbaric therapy with 1,3 atm and 24% of oxygen presents ambiguous effects. Children in the treatment group had significantly better improvements in the subscale of irritability. Additional studies are needed to investigate these results.