June 2013. Volume 9. Number 2

Should we delay the antibiotic therapy in acute otitis media in infants?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Tähtinen PA, Laine MK, Ruuskanen O, Ruohola A. Delayed versus immediate antimicrobial tratment for acute otitis media. Pediatr Infect Dis J. 2012;31(12):1227-32.
Reviewers: Llerena Santa Cruz E1, Ruiz-Canela Cáceres J2.
1Hospital Universitario Dr. Josep Trueta. Girona. Girona. España.
2CS Virgen de África. Sevilla. España.
Correspondence: Enrique Llerena Santa Cruz. Email: santum7@yahoo.com
Reception date: 10/03/2013
Acceptance date: 20/03/2013
Publication date: 03/04/2013

Abstract

Authors’ conclusions: the results indicate that delayed initiation of antimicrobial treatment does not worsen the recovery from acute otitis media, as measured by improvement during treatment. However, watchful wating before the initiation of delayed antimicrobial treatment might be associated with transient wrsenning of a child´s condition, porlongation of symptoms and economic losses.

Reviewers’ commentary: this study does not provide conclusive information regarding  the decision to treat or not acute otitis media in children between 6 months and 3 years old. Further studies are needed to establish which of these patients may benefit from delayed treatment.

How to cite this article

Llerena Santa Cruz E, Ruiz-Canela Cáceres J. ¿Debemos tratar con antibióticos de forma diferida las otitis de los lactantes? Evid Pediatr. 2013;9:25.

AVC | Critically appraised articles

Tähtinen PA, Laine MK, Ruuskanen O, Ruohola A. Delayed versus immediate antimicrobial tratment for acute otitis media. Pediatr Infect Dis J. 2012;31(12):1227-32.
Reviewers: Llerena Santa Cruz E1, Ruiz-Canela Cáceres J2.
1Hospital Universitario Dr. Josep Trueta. Girona. Girona. España.
2CS Virgen de África. Sevilla. España.
Correspondence: Enrique Llerena Santa Cruz. Email: santum7@yahoo.com
Reception date: 10/03/2013
Acceptance date: 20/03/2013
Publication date: 03/04/2013

How to cite this article

Llerena Santa Cruz E, Ruiz-Canela Cáceres J. ¿Debemos tratar con antibióticos de forma diferida las otitis de los lactantes? Evid Pediatr. 2013;9:25.

References

  1. Tähtinen PA, Laine MK, Huovinen P, Jalava J, Ruuskanen O, Ruohola A. A placebo-controlled trial of antimicrobial treatment for acute otitis media. N Engl J Med.13;364(2):116-26.
  2. Shekelle PG, Takata GS, Newberry SJ, Tumaini C, Limbos MA, Chan LS, et al. Management of Acute Otitis Media: Update. Evidence Report Technology Assessment No. 198. Rockville, MD: Agency for Healthcare Research and Quality; 2010.
  3. Lieberthal AS, Carroll AE, Chonmaitree T, Ganiats TG, Hoberman A, Jackson MA, et al. The diagnosis and management of acute otitis media. Pediatrics. 2013;131(3):e964-99.
  4. Del Castillo Martín F, Baquero Artigao F, de la Calle Cabrera T, López Robles MV, Ruiz Canela J, Alfayate Miguelez S, et al. Documento de consenso sobre etiología, diagnóstico y tratamiento de la otitis media aguda. Rev Pediatr Aten Primaria. 2012;14:195-205.
  5. National Institute for Health and Clinical Excellence. Prescribing of antibiotics for self limiting respiratory tract infections in adults and children in primary care. 2008. (Clinical guideline 69.) London: NICE; 2008.
  6. Spurling G, Del Mar C, Dooley L, Foxlee R. Administración diferida de antibióticos para las infecciones respiratorias (Revisión Cochrane traducida). En: Biblioteca Cochrane Plus 2010 Número 1. Oxford: Update Software Ltd. Disponible en: http://www.update-software.com (traducida de The Cochrane Library, 2007 Issue 3 Art no. CD004417. Chichester, UK: John Wiley & Sons, Ltd).
  7. Sanders S,  Glasziou P, Del Mar C, Rovers M. Antibióticos para la otitis media aguda en niños (Revision Cochrane traducida). En: Biblioteca Cochrane Plus 2009 Número 3. Oxford: Update Software Ltd. Disponible en: http://www.update-software.com (traducida de The Cochrane Library, 2004 Issue 1 Art no. CD000219. Chichester, UK: John Wiley & Sons, Ltd).

03/04/2013

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