September 2014. Volume 10. Number 3

How useful is xylitol to prevent episodes of acute otitis media?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Vernacchio L, Corwin MJ, Vezina RM, Pelton SI, Feldman HA, Coyne-Beasley T, et al. Xylitol syrup for the prevention of acute otitis media. Pediatrics. 2014;133:289-95.
Reviewers: García Vera C1, Llerena Santa Cruz E2.
1CS Sagasta-Ruiseñores. Zaragoza. España.
2Servicio de Pediatría. Hospital Universitario Dr. Josep Trueta. Girona. Girona. España.
Correspondence: César García Vera. Email: cgarciavera@gmail.com
Reception date: 07/05/2014
Acceptance date: 14/05/2014
Publication date: 18/06/2014

Abstract

Authors' conclusions: Viscous xylitol solution in a dose of 5 g 3 times per day was ineffective in reducing clinically diagnosed AOM among otitis-prone children.

Reviewers' commentary: This is a study, of acceptable quality and methodological design that found no differences between placebo and xylitol with respect to the number of episodes of acute otitis media. However, the preparation and administration were quite different from other studies, which found a prophylactic effect in healthy children without recurrent otitis.

How to cite this article

García Vera C, Llerena Santa Cruz E. ¿Es útil el xilitol para prevenir episodios de otitis media aguda? Evid Pediatr. 2014;10:41.

AVC | Critically appraised articles

Vernacchio L, Corwin MJ, Vezina RM, Pelton SI, Feldman HA, Coyne-Beasley T, et al. Xylitol syrup for the prevention of acute otitis media. Pediatrics. 2014;133:289-95.
Reviewers: García Vera C1, Llerena Santa Cruz E2.
1CS Sagasta-Ruiseñores. Zaragoza. España.
2Servicio de Pediatría. Hospital Universitario Dr. Josep Trueta. Girona. Girona. España.
Correspondence: César García Vera. Email: cgarciavera@gmail.com
Reception date: 07/05/2014
Acceptance date: 14/05/2014
Publication date: 18/06/2014

How to cite this article

García Vera C, Llerena Santa Cruz E. ¿Es útil el xilitol para prevenir episodios de otitis media aguda? Evid Pediatr. 2014;10:41.

References

  1. Uhari M, Kontiokari T, Koskela M, Niemelä M. Xylitol chewing gum in prevention of acute otitis media: double blind randomised trial. BMJ. 1996;313:1180-4.
  2. Azarpazhooh A, Limeback H, Lawrence HP, Shah PS. Xylitol for preventing acute otitis media in children up to 12 years of age. Cochrane Database of Systematic Reviews 2011, Issue 11. Art. No.: CD007095.
  3. Hautalahti O, Renko M, Tapiainen T, Kontiokari T, Pokka T, Uhari M. Failure of xylitol given three times a day for preventing acute otitis media. Pediatr Infect Dis J. 2007;26:423-7.
18/06/2014

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