September 2015. Volume 11. Number 3

Mumps-measles-rubella (MMR) vaccine could reduce the hospital admissions due to respiratory syncytial virus infections in developed countries

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Sørup S, Benn CS, Stensballe LG, Aaby P, Ravn H. Measles-mumps-rubella vaccination and respiratory syncytial virus-associated hospital contact. Vaccine. 2015;33:237-45.
Reviewers: Buñuel Álvarez JC1, Francisco González L2.
1CS de Villamayor de Gállego. Servicio Aragonés de Salud. Villamayor de Gállego. Zaragoza. España.
2Hospital Clínico San Carlos. Madrid. España.
Correspondence: José Cristóbal Buñuel Álvarez. Email: jcbunuel@gmail.com
Reception date: 17/07/2015
Acceptance date: 06/07/2015
Publication date: 15/07/2015

Abstract

Authors´ conclusions: MMR vaccination was associated with reduced rate of hospital contacts related to laboratory-confirmed RSV infection. Further research on the association between MMR vaccination and other unrelated pathogens are warranted.

Reviewers´ commentary: the results of this study show a non-specific protective effect of the MMR vaccine, with a decrease in the incidence of respiratory syncytal virus (RSV) infection in children, to a greater extent when more time passed from the day of vaccination. Although this is a cohort study, with the risk of bias, it meets the quality criteria required for this type of study. When informing parents about vaccines, we could tell them that the MMR vaccine could decrease the risk of serious RSV infection, an illness with high incidence in early life.

AVC | Critically appraised articles

Sørup S, Benn CS, Stensballe LG, Aaby P, Ravn H. Measles-mumps-rubella vaccination and respiratory syncytial virus-associated hospital contact. Vaccine. 2015;33:237-45.
Reviewers: Buñuel Álvarez JC1, Francisco González L2.
1CS de Villamayor de Gállego. Servicio Aragonés de Salud. Villamayor de Gállego. Zaragoza. España.
2Hospital Clínico San Carlos. Madrid. España.
Correspondence: José Cristóbal Buñuel Álvarez. Email: jcbunuel@gmail.com
Reception date: 17/07/2015
Acceptance date: 06/07/2015
Publication date: 15/07/2015

How to cite this article

Francisco González L, Buñuel Álvarez JC. La vacuna triple vírica podría disminuir los ingresos debidos a infecciones por virus respiratorio sincitial en países desarrollados. Evid Pediatr. 2015;11:44.

References

  1. Sørup S, Benn CS, Poulsen A, Krause TG, Aaby P, Ravn H. Live vaccine against measles, mumps, and rubella and the risk of hospital admissions for nontargeted infections. JAMA. 2014;31:826-35.
  2. Díez Domingo J, Ridao López M, Úbeda Sansano I, Ballester Sanz A. Incidencia y costes de la hospitalización por bronquiolitis y de las infecciones por virus respiratorio sincitial en la Comunidad Valenciana. Años 2001 y 2002. An Pediatr (Barc). 2006;65:325-30.
15/07/2015

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