July 2016. Volume 12. Number 2

The improvement in cancer treatment increases long-term survival

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Armstrong GT, Chen Y, Yasui Y, Leisenring W, Gibson TM, Mertens AC, et al. Reduction in late mortality among 5-year survivors of childhood cancer. N Engl J Med. 2016;374:833-42.

Reviewers: Pérez-Moneo Agapito B1, Rivas Fernández MÁ2.
1Hospital Universitario Infanta Leonor. Madrid. España.
2Hospital General de Cataluña. Sant Cugat del Vallés. Barcelona. España.
Correspondence: Begoña Pérez-Moneo Agapito. Email: begopma@gmail.com
Reception date: 11/06/2016
Acceptance date: 13/06/2016
Publication date: 22/06/2016

Abstract

Authors’ conclusions: recent changes in cancer treatment are associated with improvement in survival of childhood cancer. The treatments have been modified with the goal of reducing late adverse effects of both chemo- and radiotherapy.

Reviewers’ commentary: there may be an association between a longer survival in childhood cancer and the recent changes in cancer treatments. The strategy of lowering therapeutic exposure to radiotherapy and chemotherapy seems to reduce long-term adverse consequences. However, the better medical care during the last years has not been well considered.

How to cite this article

Pérez-Moneo Agapito B, Rivas Fernández MA. La mejora en los tratamientos oncológicos aumenta la supervivencia a largo plazo. Evid Pediatr. 2016;12:22.

AVC | Critically appraised articles

Armstrong GT, Chen Y, Yasui Y, Leisenring W, Gibson TM, Mertens AC, et al. Reduction in late mortality among 5-year survivors of childhood cancer. N Engl J Med. 2016;374:833-42.

Reviewers: Pérez-Moneo Agapito B1, Rivas Fernández MÁ2.
1Hospital Universitario Infanta Leonor. Madrid. España.
2Hospital General de Cataluña. Sant Cugat del Vallés. Barcelona. España.
Correspondence: Begoña Pérez-Moneo Agapito. Email: begopma@gmail.com
Reception date: 11/06/2016
Acceptance date: 13/06/2016
Publication date: 22/06/2016

How to cite this article

Pérez-Moneo Agapito B, Rivas Fernández MA. La mejora en los tratamientos oncológicos aumenta la supervivencia a largo plazo. Evid Pediatr. 2016;12:22.

References

  1. Oeffinger KC, Mertens AC, Sklar CA, Kawashima T, Hudson MM, Meadows AT, et al. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med. 2006;355:1572-82.
  2. Robison LL, Hudson MM. Survivors of childhood and adolescent cancer: life-long risks and responsibilities. Nat Rev Cancer. 2014;14:61-70.
  3. Nathan PC, Ford JS, Henderson TO, Hudson MM, Emmons KM, Casillas JN, et al. Health behaviors, medical care, and interventions to promote healthy living in the Childhood Cancer Survivor Study Cohort. J Clin Oncol. 2009;27:2363-73.
  4. MacArthur AC, Spinelli JJ, Rogers PC, Goddard KJ, Abanto ZU, McBride ML. Mortality among 5-year survivors of cancer diagnosed during childhood or adolescence in British Columbia, Canada. Pediatr Blood Cancer. 2007;48:460-7.
  5. Guía de detección temprana del cáncer infantil. En: Asociación Española de Pediatría [en línea] [consultado el 13/06/2016]. Disponible en: http://guiadeteccioncancerinfantil.aepap.org
22/06/2016

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