December 2019. Volume 15. Number 4

Continuous perfusion of vancomycin for premature infants. Has the time come to start with it?

 
 
 
 
 
 
 
 
 
 
Rating: 0 (0 Votes)
Newsletter Free Subscription
Regularly recieve most recent articles by e-mail
Subscribe
Print
Add to library
Discuss this article

AVC | Critically appraised articles

Gwee A, Cranswick N, McMullan B, Perkins E, Bolisetty S, Gardiner K, et al. Continuous versus intermittent vancomycin infusions in infants: a randomized controlled trial. Pediatrics. 2019;143:e20182179.

Reviewers: Rivas Fernández MÁ1, Aparicio Sánchez JL2.
1Hospital Universitario General de Cataluña. Sant Cugat del Vallés. Barcelona. España.
2Servicio de Pediatría. Hospital Dr. José Molina Orosa. Lanzarote. Las Palmas. España.
Correspondence: Mª Ángeles Rivas Fernández. Email: mayrivas5@gmail.com
Reception date: 11/11/2019
Acceptance date: 25/11/2019
Publication date: 18/12/2019

Abstract

Authors’ conclusions: the continuous perfusion of vancomycin succeeds in improving the results of the current standard procedure of intermittent administration, in terms of achievements of target concentrations, with the addition of also requiring lower total daily doses to reach the desired concentration, and without being able to find associated adverse effects.

Reviewers’ commentary: although the results seem very encouraging, this work contains limitations that, for the time being, would not allow us to guarantee that continuous infusion of vancomycin is a safe alternative, nor to affirm that it is cost-effective.

How to cite this article

Rivas Fernández MA, Aparicio Sánchez JL. Vancomicina en perfusión continua para los recién nacidos prematuros. ¿Llegó el momento? Evid Pediatr. 2019;15:51.

AVC | Critically appraised articles

Gwee A, Cranswick N, McMullan B, Perkins E, Bolisetty S, Gardiner K, et al. Continuous versus intermittent vancomycin infusions in infants: a randomized controlled trial. Pediatrics. 2019;143:e20182179.

Reviewers: Rivas Fernández MÁ1, Aparicio Sánchez JL2.
1Hospital Universitario General de Cataluña. Sant Cugat del Vallés. Barcelona. España.
2Servicio de Pediatría. Hospital Dr. José Molina Orosa. Lanzarote. Las Palmas. España.
Correspondence: Mª Ángeles Rivas Fernández. Email: mayrivas5@gmail.com
Reception date: 11/11/2019
Acceptance date: 25/11/2019
Publication date: 18/12/2019

How to cite this article

Rivas Fernández MA, Aparicio Sánchez JL. Vancomicina en perfusión continua para los recién nacidos prematuros. ¿Llegó el momento? Evid Pediatr. 2019;15:51.


Related Articles

CA | Vancomicina en perfusión continua en neonatos: una opción prometedora

Pérez Méndez C. Vancomicina en perfusión continua en neonatos: una opción prometedora. Evid Pediatr. 2019;15:52.
18/12/2019

Linked Comment

CA | Vancomicina en perfusión continua en neonatos: una opción prometedora

Pérez Méndez C. Vancomicina en perfusión continua en neonatos: una opción prometedora. Evid Pediatr. 2019;15:52.