March 2020. Volume 16. Number 1

Celiac disease and high intake of gluten: doubtful relationship

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Lund-Blix NA, Mårild K, Tapia G, Norris JM, Stene LC, Størdal K. Gluten intake in early childhood and risk of celiac disease in childhood: a nationwide cohort study. Am J Gastroenterol. 2019;114:1299-306.

Reviewers: Aizpurua Galdeano P1, Aparicio Rodrigo M2.
1Pediatra. CS Ondarreta. San Sebastián. Guipúzcoa. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 13/01/2020
Acceptance date: 04/02/2020
Publication date: 12/02/2020

Abstract

Authors’ conclusions: a higher amount of gluten in the diet at 18 months was a risk factor for childhood onset Celiac disease in a general population cohort. The association was independent of when gluten was introduced in the infant diet.

Reviewers’ commentary: the results of this study suggest that children in the general population who ingest high amounts of gluten at 18 months have a higher risk of developing celiac disease later in childhood. However, methodological problems and the small increase in risk, which does not explain the increase in the prevalence of the disease in recent years, do not allow us to recommend changes in our practice based solely on the results of this study.

How to cite this article

Aizpurua Galdeano P, Aparicio Rodrigo M. Celiaquía y alta ingesta de gluten: dudosa relación. Evid Pediatr. 2020;16:9.

AVC | Critically appraised articles

Lund-Blix NA, Mårild K, Tapia G, Norris JM, Stene LC, Størdal K. Gluten intake in early childhood and risk of celiac disease in childhood: a nationwide cohort study. Am J Gastroenterol. 2019;114:1299-306.

Reviewers: Aizpurua Galdeano P1, Aparicio Rodrigo M2.
1Pediatra. CS Ondarreta. San Sebastián. Guipúzcoa. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 13/01/2020
Acceptance date: 04/02/2020
Publication date: 12/02/2020

How to cite this article

Aizpurua Galdeano P, Aparicio Rodrigo M. Celiaquía y alta ingesta de gluten: dudosa relación. Evid Pediatr. 2020;16:9.

12/02/2020

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