December 2020. Volume 16. Number 4

There is insufficient evidence to establish optimal doses of polyethylene glycol in the infant

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Rachel H, Griffith AF, Teague WJ, Hutson JM, Gibb S, Goldfeld S, et al. Polyethylene Glycol Dosing for Constipation in Children Younger Than 24 Months: A Systematic Review. J Pediatr Gastroenterol Nutr. 2020;71:171-5.

Reviewers: Ochoa Sangrador C1, Andrés de Llano JM2.
1Servicio de Pediatría. Complejo Asistencial de Zamora. Zamora. España.
2Servicio de Pediatría. Complejo Asistencial Universitario de Palencia. Palencia. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas2@gmail.com
Reception date: 12/09/2020
Acceptance date: 05/10/2020
Publication date: 21/10/2020

Abstract

Authors' conclusions: this systematic review provides information on the low risk of polyethylene glycol side effects in children younger than 24 months with functional constipation. However, there is no evidence to establish the appropriate dose.

Reviewers' commentary: polyethylene glycol dosing recommendations for functional constipation in infants are based on clinical practice, since there are hardly any experimental studies at this age. It seems sensible to start treatment with medium-low doses, resorting to higher doses according to the response and tolerance.

How to cite this article

Ochoa Sangrador C, Andrés de Llano JM. No hay evidencia suficiente para establecer la dosis óptima de polietilenglicol en el lactante. Evid Pediatr. 2020;16:44.

AVC | Critically appraised articles

Rachel H, Griffith AF, Teague WJ, Hutson JM, Gibb S, Goldfeld S, et al. Polyethylene Glycol Dosing for Constipation in Children Younger Than 24 Months: A Systematic Review. J Pediatr Gastroenterol Nutr. 2020;71:171-5.

Reviewers: Ochoa Sangrador C1, Andrés de Llano JM2.
1Servicio de Pediatría. Complejo Asistencial de Zamora. Zamora. España.
2Servicio de Pediatría. Complejo Asistencial Universitario de Palencia. Palencia. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas2@gmail.com
Reception date: 12/09/2020
Acceptance date: 05/10/2020
Publication date: 21/10/2020

How to cite this article

Ochoa Sangrador C, Andrés de Llano JM. No hay evidencia suficiente para establecer la dosis óptima de polietilenglicol en el lactante. Evid Pediatr. 2020;16:44.

21/10/2020

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