September 2021. Volume 17. Number 3

Combination of symbiotics Lactobacillus spp. and Bifidobacterium seems the most effective in the treatment of preterm infants

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Chi C, Li C, Buys N, Wang W, Yin C, Sun J. Effects of Probiotics in Preterm Infants: A Network Meta-analysis. Pediatrics. 2021:147:e20200706.

Reviewers: Carvajal Encina F1, Aparicio Rodrigo M2.
1UPC Neonatal. Hospital La Serena. Facultad de Medicina. Universidad Católica del Norte. Coquimbo. Chile.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 02/07/2021
Acceptance date: 13/07/2021
Publication date: 28/07/2021

Abstract

Authors’ conclusions: the efficacy of single probiotic supplements is limited, compared to combined use of probiotics. To achieve optimal effect on premature infant health, combined use of prebiotic and probiotic, especially Lactobacillus or Bifidobacterium, is recommended.

Reviewers’ commentary: this study shows that the use of synbiotics in premature infants seems to be beneficial, especially the combined use of Lactobacillus spp. and Bifidobacterium spp. However, these results should be taken with caution before translating them into clinical practice, as the most appropriate dose and time of treatment and efficacy in the most immature infants cannot yet be cdetermined.

How to cite this article

Carvajal Encina F, Aparicio Rodrigo M. La combinación de simbióticos Lactobacillus spp. y Bifidobacterium parece la más eficaz en el tratamiento de recién nacidos prematuros. Evid Pediatr. 2021;17:29.

AVC | Critically appraised articles

Chi C, Li C, Buys N, Wang W, Yin C, Sun J. Effects of Probiotics in Preterm Infants: A Network Meta-analysis. Pediatrics. 2021:147:e20200706.

Reviewers: Carvajal Encina F1, Aparicio Rodrigo M2.
1UPC Neonatal. Hospital La Serena. Facultad de Medicina. Universidad Católica del Norte. Coquimbo. Chile.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 02/07/2021
Acceptance date: 13/07/2021
Publication date: 28/07/2021

How to cite this article

Carvajal Encina F, Aparicio Rodrigo M. La combinación de simbióticos Lactobacillus spp. y Bifidobacterium parece la más eficaz en el tratamiento de recién nacidos prematuros. Evid Pediatr. 2021;17:29.

28/07/2021

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