March 2022. Volume 18. Number 1

A new strategy against Malaria. Seasonal chemoprophylaxis combined with malaria vaccination

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Chandramohan D, Zongo I, Sagara I, Cairns M, Yerbanga RS, Diarra M, et al. Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention. N Engl J Med. 2021;385:1005-17.

Reviewers: Aizpurua Galdeano P1, Flores Villar S2.
1Pediatra. CS Ondarreta. San Sebastián. Guipúzcoa. España.
2Pediatra. Área de Hospitalización Pediátrica. Hospital Universitario MútuaTerrassa. Barcelona. España.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 14/03/2022
Acceptance date: 22/03/2022
Publication date: 31/03/2022

Abstract

Authors´ conclusions: The use of malaria chemoprophylaxis in conjunction with the malaria vaccine clearly reduces the incidence of uncomplicated malaria, severe malaria, and death from malaria, and outperforms any other preventive intervention option against malaria.

Reviewers´ commentary: In this study, the RTS, S / AS01 vaccine has protected against uncomplicated malaria infection in a way that is not inferior to chemoprophylaxis, and the joint administration of both treatments has produced a greater decrease in the incidence of the disease than each one separately. Currently, and pending the appearance of new vaccines and more effective treatments, the strategy of associating the different treatments available to reduce the burden of malaria in countries with moderate or high transmission seems appropriate.

How to cite this article

Aizpurua Galdeano P. Flores Villar S. Nueva estrategia contra el paludismo. Quimioprofilaxis estacional junto con la vacunación antimalárica. Evid Pediatr. 2022;18:9.

AVC | Critically appraised articles

Chandramohan D, Zongo I, Sagara I, Cairns M, Yerbanga RS, Diarra M, et al. Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention. N Engl J Med. 2021;385:1005-17.

Reviewers: Aizpurua Galdeano P1, Flores Villar S2.
1Pediatra. CS Ondarreta. San Sebastián. Guipúzcoa. España.
2Pediatra. Área de Hospitalización Pediátrica. Hospital Universitario MútuaTerrassa. Barcelona. España.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 14/03/2022
Acceptance date: 22/03/2022
Publication date: 31/03/2022

How to cite this article

Aizpurua Galdeano P. Flores Villar S. Nueva estrategia contra el paludismo. Quimioprofilaxis estacional junto con la vacunación antimalárica. Evid Pediatr. 2022;18:9.

31/03/2022

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