September 2011. Volume 7. Number 3

Creatine, a hope for muscular dystrophy?

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Kley RA, Tarnopolsky MA, Vorgerd M. Creatine for treating muscle disorders. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD004760.
Reviewers: Fernández Rodríguez M1, Orejón de Luna G2.
1Centro de Salud de Potes. Madrid. España.
2CS General Ricardos. Madrid. España.
Correspondence: Mercedes Fernández Rodríguez. Email: mer763@hotmail.com
Reception date: 04/05/2011
Acceptance date: 24/05/2011
Publication date: 15/06/2011

Abstract

Authors' conclusions: oral creatine improves muscle strength in muscular dystrophies but this effect could not be demonstrated in metabolic myopathies. No adverse effects were detected except inMcArdle's disease.

Reviewers' commentary: creatine may have a role in the treatment of muscular dystrophy. It is necessary to know in which stages of the disease it would be indicated, the long-term effect and the possible combination with other treatments.

How to cite this article

Fernández Rodríguez M, Orejón de Luna G. La creatina: ¿una esperanza para las distrofias musculares? Evid Pediatr. 2011;7:57.

AVC | Critically appraised articles

Kley RA, Tarnopolsky MA, Vorgerd M. Creatine for treating muscle disorders. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD004760.
Reviewers: Fernández Rodríguez M1, Orejón de Luna G2.
1Centro de Salud de Potes. Madrid. España.
2CS General Ricardos. Madrid. España.
Correspondence: Mercedes Fernández Rodríguez. Email: mer763@hotmail.com
Reception date: 04/05/2011
Acceptance date: 24/05/2011
Publication date: 15/06/2011

How to cite this article

Fernández Rodríguez M, Orejón de Luna G. La creatina: ¿una esperanza para las distrofias musculares? Evid Pediatr. 2011;7:57.

References

  1. Kley RA, Vorgerd M, Tarnopolsky MA. Creatine for treating muscle disorders. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No.: CD004760. DOI: 10.1002/14651858.CD004760.pub2.
  2. Neuromuscular symptom and disability score [en línea] [fecha de consulta: 21-IV-2011]. Disponible en: http://www.researchrom.com/masterlist/view/9#form2
  3. Banerjee B, Sharma U, Balasubramanian K, Kalaivani M, Kalra V, Jagannathan NR. Effect of creatine monohydrate in improving cellular energetics and muscle strength in ambulatory Duchenne muscular dystrophy patients:a randomized, placebo-controlled 31P MRS study. Magn Reson Imaging. 2010;28:698-707.
15/06/2011

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