Authors’ conclusions: zinc reduces the duration and severity of the common cold in healthy people. When supplemented for at least ﬁve months, it reduces cold incidence, school absenteeism and prescription of antibiotics in children. There are potential side effects. In view of this and the differences in study populations, dosages, formulations and duration of treatment, it is difﬁcult to make ﬁrm recommendations about the dose, formulation and duration that should be used.
Reviewers’ commentary: though the initial results are promising, given the collateral disagreeable effects and the lack of efficacy of some formulations, a general recommendation for zinc in treatment of the common cold should not be done.