July 2021. Volume 17. Number 2

In children with whooping cough, a positive PCR for Mycoplasma pneumoniae must be interpreted with caution

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Desjardins M, Doyon-Plourde P, Mousseau S, Iachimov D, Rallu F, Quach C. Multiplex Polymerase Chain Reaction Panel for Suspected Pertussis: What About a Positive Mycoplasma pneumoniae Result? Pediatr Infect Dis J. 2019;38:1015-9.

Reviewers: Carvajal Encina F1, Gimeno Díaz de Atauri Á2.
1Facultad de Medicina. Universidad Católica del Norte. Coquimbo. Chile.
2Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 17/03/2021
Acceptance date: 08/04/2021
Publication date: 14/04/2021

Abstract

Authors’ conclusions: in pediatric patients with suspected pertussis, there are differences between those with positive PCR for Mycoplasma pneumoniae and those with positive PCR for Bordetella according to clinical presentation. Either way, there are no relevant differences when patients with confirmed Mycoplasma infection are compared with the negative PCR group. The impact of this findings in terms of patient outcomes is unclear.

Reviewers’ commentary: the interpretation of a positive PCR for Mycoplasma pneumoniae in children with suspected pertussis is difficult due to the possibility of carrier status, a high frequency of coinfections in some contexts and the absence of correlation with relevant clinical variables. More research is required.

How to cite this article

Carvajal Encina F, Gimeno Díaz de Atauri A. En niños con tosferina, la interpretación de una PCR positiva para Mycoplasma pneumoniae debe ser cautelosa. Evid Pediatr. 2021;17:17.

AVC | Critically appraised articles

Desjardins M, Doyon-Plourde P, Mousseau S, Iachimov D, Rallu F, Quach C. Multiplex Polymerase Chain Reaction Panel for Suspected Pertussis: What About a Positive Mycoplasma pneumoniae Result? Pediatr Infect Dis J. 2019;38:1015-9.

Reviewers: Carvajal Encina F1, Gimeno Díaz de Atauri Á2.
1Facultad de Medicina. Universidad Católica del Norte. Coquimbo. Chile.
2Servicio de Pediatría. Hospital Universitario 12 de Octubre. Madrid. España.
Correspondence: Fernando Carvajal Encina. Email: fcarvajal@ucn.cl
Reception date: 17/03/2021
Acceptance date: 08/04/2021
Publication date: 14/04/2021

How to cite this article

Carvajal Encina F, Gimeno Díaz de Atauri A. En niños con tosferina, la interpretación de una PCR positiva para Mycoplasma pneumoniae debe ser cautelosa. Evid Pediatr. 2021;17:17.

14/04/2021

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