Área Clínica |
Referencia bibliográfica |
Puntuación |
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Tratamiento | Savarirayan R, De Bergua JM, Arundel P, Salles JP, Saraff V, Delgado B, et al. Oral Infigratinib Therapy in Children with Achondroplasia. N Engl J Med. 2025;392(9):865-74. | 37 |
Storgaard Petersen R, Hallas H, Brustad N, Chawes B. Short-term efficacy of inhaled short-acting beta-2-agonists for acute wheeze/asthma symptoms in preschool-aged children: a systematic review and meta-analysis. Thorax. 2025;80(6):349-57. | 37 | |
Jiang M, Zhang Y, Liu T, Hong X, Kho AT, Li J, et al. Circulating miRNAs and childhood asthma ICS response: a stratified analysis in the intervention arm of an RCT with vitamin D effect modification. Thorax. 2025-thorax-2024-222618. | 36 | |
Murai H, Kawamoto N, Arima T, Okada Y, Takeuchi H, Miyamoto M, et al. New topical molecular targeted therapies for atopic dermatitis in children: A systematic review and meta-analysis. Pediatr Allergy Immunol. 2025;36(6):e70122. | 39 | |
Tachdjian R, Banerji A, Busse PJ, Agmon-Levin N, Anderson J, Cancian M, et al. Effective long-term prophylaxis with lanadelumab in adolescents with hereditary angioedema: EMPOWER/ENABLE. Pediatr Allergy Immunol. 2025;36(4):e70072. | 37 | |
Ball GDC, Merdad R, Birken CS, Cohen TR, Goodman B, Hadjiyannakis S, et al. Managing obesity in children: a clinical practice guideline. CMAJ. 2025;197(14):E372-E389. | 41 | |
Carlo WA, Eichenwald EC, Carper BA, Bell EF, Keszler M, Patel RM, et al. Extended Caffeine for Apnea in Moderately Preterm Infants: The MoCHA Randomized Clinical Trial. JAMA. 2025;333(24):2154-63. | 36 | |
Boutin A, Colaco K, Stimec J, Camp M, Narayanan U, Bhatt M, et al. Removable Boot vs Casting of Toddler's Fractures: A Randomized Clinical Trial. JAMA Pediatr. 2025;179(7):713-21. | 37 | |
Mullaly R, Smith A, Murphy C, Armstrong S, Zakharchenko L, Franklin O, et al. Does early-targeted risk-based management of a patent ductus arteriosus improve outcomes in preterm infants? Insights from an observational study. BMJ Paediatr Open. 2025;9(1):e003347. | 29 | |
Iramain R, Jara A, Ortiz J, Cardozo L, Morinigo R. Lactobacillus reuteri protectis DSM 17938 at high doses versus placebo in children with acute gastroenteritis in a Pediatric Emergency Department. J Pediatr Gastroenterol Nutr.2025;80:760-6. | 42 | |
Utsunomiya H, Tanaka K, Okubo H, Nagata C, Miyake Y. Association between dairy product intake and prevalence of dental caries in 3-year-old Japanese children. J Pediatr Gastroenterol Nutr.2025;80:714-22. | 40 | |
Perramon-Malavez A, Hermosilla E, Coma E, Fina F, Reñé A, Martínez-Marcos M, et al. Effectiveness of Nirsevimab Immunoprophylaxis Against Respiratory Syncytial Virus-related Outcomes in Hospital Care Settings: A Seasonal Cohort Study of Infants in Catalonia, Spain. Pediatr Infect Dis J. 2025;44(5):394-8. | 35 | |
Palomino-Fernandez L, Villarejo-Perez A, Fernandez-Fuentes C, Sanchez-Codez MI, Del Valle-De Leon N, Gallego-Gutierrez S, et al. Could Intravenous Immunoglobulin Be an Alternative Therapy for Treating Infant Botulism in Areas Where Human Botulism Immunoglobulin Is Not Easily Available?: Our Experience in Andalusia, Spain. Pediatr Infect Dis J. 2025;44(6):e193-e198. | 34 | |
Abdelgadir IS, Mudawi K, Hamud A, Tonbari A, Alhaji A, Salem R, et al. Second-line treatment option for children aged 18 years and under with an acute severe asthma exacerbation: a systematic review and meta-analysis of randomised controlled trials. Arch Dis Child. 2025;archdischild-2024-327838. | 44 | |
Miroshnychenko A, Ibrahim S, Roldan Y, Kulatunga-Moruzi C, Montante S, Couban R, et al. Gender affirming hormone therapy for individuals with gender dysphoria aged <26 years: a systematic review and meta-analysis. Arch Dis Child. 2025;110(6):437-45. | 37 | |
Bandell A, Giles L, Cervelo Bouzo P, Sibbring GC, Maniaci J, Wojtczak H, et al. Safety of LAIV Vaccination in Asthma or Wheeze: A Systematic Review and GRADE Assessment. Pediatrics. 2025;155:e2024068459. | 40 | |
Finch-Edmondson M, Paton MCB, Webb A, Reza Ashrafi M, Blatch-Williams RK, Cox CS Jr, et al. Cord Blood Treatment for Children With Cerebral Palsy: Individual Participant Data Meta-Analysis. Pediatrics. 2025;155:e2024068999. | 40 | |
O'Hare K, Byrne JF, Ramsay H, Romaniuk L, McGrath J, Keating D, et al. Stimulant Medication Use and Risk of Psychotic Experiences. Pediatrics. 2025;155:e2024069142. | 37 | |
Ramgopal S, Michelson KA. Adoption of Dexamethasone for Asthma Exacerbations. Pediatrics. 2025;156:e2024070153. | 26 | |
Xu Y, Zhuang D, Chen F, Ma L, Du H, Jin A, et al. Nonsurgical Therapies for Spastic Cerebral Palsy: A Network Meta-Analysis. Pediatrics. 2025;156:e2024070402. | 36 | |
Sethi NJ, Carlsen ELM, Tabassum A, Cortes D, Mark Øw S, Schmidt IM, et al. Efficacy and safety of individualised versus standard 10-day antibiotic treatment in children with febrile urinary tract infection (INDI-UTI): a pragmatic, open-label, multicentre, randomised, controlled, non-inferiority trial in Denmark. Lancet Infect Dis. 2025;25:925-35. | 37 | |
Chaccour C, Maia M, Kariuki M, Ruiz-Castillo P, Wanjiku C, Kasiwa L, et al. Ivermectin to Control Malaria - A Cluster-Randomized Trial. N Engl J Med. 2025;393(4):362-75. | 44 | |
Freedman SB, Williamson-Urquhart S, Plint AC, Dixon A, Beer D, Joubert G, et al; Pediatric Emergency Research Canada Innovative Clinical Trials Study Group. Multidose Ondansetron after Emergency Visits in Children with Gastroenteritis. N Engl J Med. 2025;393(3):255-66. | 37 | |
LaForce C, Albers F, Danilewicz A, Jeynes-Ellis A, Kraft M, Panettieri RA Jr, et al; BATURA Investigators. As-Needed Albuterol-Budesonide in Mild Asthma. N Engl J Med. 2025;393(2):113-24. | 29 | |
Etiología | Marczak H, Krenke K, Griese M, Peradzyńska J, Lange J, Kulus M, et al. Diagnostic Evaluation and Clinical Findings in Children With Persistent Tachypnea of Infancy and Neuroendocrine Cell Hyperplasia of Infancy: A European Multicenter Retrospective Study. Chest. 2025;168(1):171-82. | 28 |
Garrido-Muñoz F, Fernández-Vega A, Gregorio-Hernández R, Padín-Fontán M, Heras-Martín ML, Teresa-Palacio M, et al. Proteomic Analysis of Nasopharyngeal Aspirate Biomarkers for Prematurity-Related Bronchopulmonary Dysplasia. Chest, 2025;S0012-3692(25)00562-8. | 38 | |
Wintzell V, Brenner P, Halldner L, Rhedin S, Gong T, Almqvist C. Montelukast Use and the Risk of Neuropsychiatric Adverse Events in Children. JAMA Pediatr. 2025;179(4):418-27. | 43 | |
Cheng Y, Zhang M, Zheng H, Yu Q, Wei H, Xue R, et al. Ambient formaldehyde combined with high temperature exposure and respiratory disease admissions among children: a time-series study across multiple cities. Thorax. 2025;80(7):457-65. | 35 | |
Zhang X, Hartman TJ, Adgent M, Moore P, Gebretsadik T, Nickelberry M, et al. . Maternal prenatal carotenoids and child lung function: exploration of modifying factors. Thorax. 2025;80(10):748-55. | 35 | |
Rutter CE, Mpairwe H , Figueiredo CA, Njoroge M, Robertson S, Ali H, et al. ; CAMERA Study Group . Risk factors for atopic and non-atopic asthma in school-age children from high-income and low- and middle-income countries. Thorax. 2025:thorax-2024-222118. | 28 | |
Madhi SA, Ceballos A, Cousin L, Domachowske JB, Langley JM, Lu E, et al. Population Attributable Risk of Wheeze in 2-<6-Year-old Children, Following a Respiratory Syncytial Virus Lower Respiratory Tract Infection in The First 2 Years of Life. Pediatr Infect Dis J. 2025;44(5):379-86. | 30 | |
Otras áreas | Wood CL, Lane LC, Barlow H, Drake AJ, Kanthagnany SK, Pearce MS, et al. Symptomatic glucocorticoid-induced adrenal suppression in the United Kingdom and Ireland: a BPSU study. Arch Dis Child. 2025 ;110(5):363-68. | 32 |
Pronóstico | Wadhwa V, Dharmage SC, Wurzel D, Sly PD, Svanes C, Lowe AJ, et al. Early-life allergic sensitization and respiratory infection-Two hits on lung function? Pediatr Allergy Immunol. 2025 ;36(6):e70115. | 37 |
John S, Young LT, Lacro RV, Hoskoppal A, Ou Z, Presson AP, et al. Extracardiac Manifestations Fail to Predict the Severity of Cardiac Phenotype in Children and Young Adults with Marfan Syndrome. Pediatr Cardiol. 2025;46(4):828-34. | 36 | |
Wang Y, Wang L, Zang H, Wang J, Wu H, Zhao W. Comparison of Different Ultrasonic Screening Methods and Analysis of High Risk Factors for Fetal Cardiac Malformation in Second Trimester of Pregnancy. Pediatr Cardiol. 2025;46(4):769-77. | 35 | |
Lo D, Lawson C, Broomfield J, Gillies C, Shabnam S, Gaillard EA, et al. Risk factors for recurrent attacks of wheeze in preschool children: a population-based cohort study in England. Arch Dis Child. 2025:archdischild-2024-328375. | 41 | |
Hymel E, Kabayundo J, Napit K, Watanabe-Galloway S. Persistent Poverty and Pediatric Cancer Survival. Pediatrics. 2025;155:e2024069973. | 34 | |
Patnode CD, Henrikson NB, Webber EM, Blasi PR, Senger CA, Guirguis-Blake JM. Breastfeeding and Health Outcomes for Infants and Children: A Systematic Review. Pediatrics. 2025;156:e2025071516. | 31 |
Otros artículos seleccionados y no valorados críticamente. Evid Pediatr. 2025;21:38.