One dose of ondansetron seems to reduce vomiting in patients with acute gastroenteritis attended in emergency departments" />

December 2008. Volume 4. Number 4

One dose of ondansetron seems to reduce vomiting in patients with acute gastroenteritis attended in emergency departments

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

DeCamp LR, Byerley JS, Doshi N, Steiner MJ. Use of antiemetic agents in acute gastroenteritis: a systematic review and meta-analysis. Arch Pediatr Adolesc Med. 2008;162:858-65
Reviewers: Ochoa Sangrador C1, Orejón de Luna G2.
1Servicio de Pediatrí­a. Hospital Virgen de la Concha. Zamora. España.
2CS General Ricardos. Madrid. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas@meditex.es
Reception date: 23/10/2008
Acceptance date: 28/10/2008
Publication date: 01/12/2008

Abstract

Authors' conclusions: ondansetron therapy decreases the risk of persistent vomiting, hospital admissions and the use of intravenous fluid, in children with vomiting due to gastroenteritis. Treatment guidelines should incorporate ondansetron for the therapy of selected childrens with gastroenteritis.

Reviewers' comantary: despite the fact that ondansetron appears to reduce the vomiting of patients with gastroenteritis, the information provided by this review does not clear up some doubts that question its widespread application in clinical practice. It would be necessary to conduct more studies that include a broader spectrum of patients and evaluating the benefit of treatment on the patient.

How to cite this article

Ochoa Sangrador C, Orejón de Luna G. Una dosis de ondansetrón parece reducir los vómitos en pacientes con gastroenteritis aguda atendidos en servicios de urgencias. Evid Pediatr. 2008;4:73.

AVC | Critically appraised articles

DeCamp LR, Byerley JS, Doshi N, Steiner MJ. Use of antiemetic agents in acute gastroenteritis: a systematic review and meta-analysis. Arch Pediatr Adolesc Med. 2008;162:858-65
Reviewers: Ochoa Sangrador C1, Orejón de Luna G2.
1Servicio de Pediatrí­a. Hospital Virgen de la Concha. Zamora. España.
2CS General Ricardos. Madrid. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas@meditex.es
Reception date: 23/10/2008
Acceptance date: 28/10/2008
Publication date: 01/12/2008

How to cite this article

Ochoa Sangrador C, Orejón de Luna G. Una dosis de ondansetrón parece reducir los vómitos en pacientes con gastroenteritis aguda atendidos en servicios de urgencias. Evid Pediatr. 2008;4:73.

References

  1. Szajewska H, Gieruszczak-Bia?ek D, Dylag M.Meta-analysis: ondansetron for vomiting in acute gastroenteritis in children. Aliment Pharmacol Ther. 2007;25:393-400.
  2. Alhashimi D, Alhashimi H, Fedorowicz Z. Antieméticos para reducir los vómitos relacionados con la gastroenteritis aguda en niños y adolescentes (Revisión Cochrane traducida). En: La Biblioteca Cochrane Plus, 2008 Número 2. Oxford: Update Software Ltd. Disponible en: http://www.update-software.com. (Traducida de The Cochrane Library, 2008 Issue 2. Chichester, UK: John Wiley & Sons, Ltd.). [3]
  3. Freedman SB, Adler M, Seshadri R, Powell EC. Oral ondansetron for gastroenteritis in a pediatric emergency department. New England Journal of Medicine. 2006;354:1698-705.
01/12/2008

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