December 2019. Volume 15. Number 4

Bivalent vaccination against HPV reduces the risk of cervical disease

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Palmer T, Wallace L, Pollock KG, Cuschieri K, Robertson C, Kavanagh K, et al. Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12-13 in Scotland: retrospective population study. BMJ. 2019 Apr 3;365:l1161.

Reviewers: Albi Rodríguez MS1, Esparza Olcina MJ2.
1Servicio de Neumología y Alergia Infantil. Hospital Universitario 12 de Octubre. Madrid. España.
2Pediatra. CS Barcelona. Móstoles. Madrid. España.
Correspondence: María Salomé Albi Rodríguez. Email: msalbir@gmail.com
Reception date: 24/09/2019
Acceptance date: 04/10/2019
Publication date: 16/10/2019

Abstract

Authors’ conclusions: routine immunization at 12-13 years with three doses of bivalent HPV vaccine is associated to an important reduction in cervical disease 7 years later, measured with cytology and histology. Reduction in non-vaccinated women was also observed, probably due to herd protection.

Reviewers’ commentary: in practice, the efficacy achieved with bivalent HPV routine vaccination in populations with good vaccine coverage, is high. The results obtained from this study could lead to consider future modifications in population-based cancer screening among groups with optimum coverage.

How to cite this article

Albi Rodríguez MS, Esparza Olcina MJ. La vacuna bivalente frente a VPH reduce el riesgo de desarrollo de lesiones cervicales. Evid Pediatr. 2019;15:48.

AVC | Critically appraised articles

Palmer T, Wallace L, Pollock KG, Cuschieri K, Robertson C, Kavanagh K, et al. Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12-13 in Scotland: retrospective population study. BMJ. 2019 Apr 3;365:l1161.

Reviewers: Albi Rodríguez MS1, Esparza Olcina MJ2.
1Servicio de Neumología y Alergia Infantil. Hospital Universitario 12 de Octubre. Madrid. España.
2Pediatra. CS Barcelona. Móstoles. Madrid. España.
Correspondence: María Salomé Albi Rodríguez. Email: msalbir@gmail.com
Reception date: 24/09/2019
Acceptance date: 04/10/2019
Publication date: 16/10/2019

How to cite this article

Albi Rodríguez MS, Esparza Olcina MJ. La vacuna bivalente frente a VPH reduce el riesgo de desarrollo de lesiones cervicales. Evid Pediatr. 2019;15:48.

16/10/2019

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