June 2020. Volume 16. Number 2

Efficacy of a tetravalent dengue vaccine in healthy children and adolescents

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Biswal S, Reynales H, Sáez-Llorens X, López P, Borja-Tabora C, Kosalaraksa P, et al. Efficacy of a Tetravalent Dengue Vaccine in Healthy Children and Adolescents. N Engl J Med. 2019;381:2009-2019.

Reviewers: Ochoa Sangrador C1, Andrés de Llano JM2.
1Servicio de Pediatría. Complejo Asistencia de Zamora. Zamora. España.
2Servicio de Pediatría. Complejo Asistencial Universitario de Palencia. Palencia. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas2@gmail.com
Reception date: 15/02/2020
Acceptance date: 11/03/2020
Publication date: 08/04/2020

Abstract

Conclusions of the authors of the study: tetravalent dengue vaccine (TAK-003) was efficacious against symptomatic dengue in countries in which the disease is endemic.

Reviewers’ comment: preliminary data suggest that the TAK-003 vaccine is efficacious and safe to prevent dengue. Although the vaccine would not be indicated in Spain, as it is not an endemic zone, it would be applicable in regions of America or Asia, as well as for travelers who are going to travel to risk areas.

How to cite this article

Ochoa Sangrador C, Andrés de Llano JM. Eficacia de una vacuna tetravalente contra el dengue en niños y adolescentes sanos. Evid Pediatr. 2020;16:17.

AVC | Critically appraised articles

Biswal S, Reynales H, Sáez-Llorens X, López P, Borja-Tabora C, Kosalaraksa P, et al. Efficacy of a Tetravalent Dengue Vaccine in Healthy Children and Adolescents. N Engl J Med. 2019;381:2009-2019.

Reviewers: Ochoa Sangrador C1, Andrés de Llano JM2.
1Servicio de Pediatría. Complejo Asistencia de Zamora. Zamora. España.
2Servicio de Pediatría. Complejo Asistencial Universitario de Palencia. Palencia. España.
Correspondence: Carlos Ochoa Sangrador. Email: cochoas2@gmail.com
Reception date: 15/02/2020
Acceptance date: 11/03/2020
Publication date: 08/04/2020

How to cite this article

Ochoa Sangrador C, Andrés de Llano JM. Eficacia de una vacuna tetravalente contra el dengue en niños y adolescentes sanos. Evid Pediatr. 2020;16:17.

08/04/2020

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