September 2021. Volume 17. Number 3

Zinc supplements in premature infants: no clear evidence on its usefulness

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Staub E, Evers K, Askie LM. Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates. Cochrane Database Syst Rev. 2021;3:CD012797.

Reviewers: Ortega Páez E1, Flores Villar S2.
1Pediatra. UGC de Maracena. Distrito Granada-Metropolitano. Granada. España.
2Unidad de Hospitalización Pediátrica. Hospital Universitario MútuaTerrassa. Barcelona. España.
Correspondence: Eduardo Ortega Páez. Email: edortegap@gmail.com
Reception date: 31/08/2021
Acceptance date: 14/09/2021
Publication date: 29/09/2021

Abstract

Authors’ conclusions: enteral zinc supplementation in preterm infants may moderately decrease mortality and probably improve weight gain and linear growth in the short term, but may have little or no effect on the common morbidities of prematurity. There are no data to assess the effect of zinc supplementation on long-term neurodevelopment.

Reviewers’ commentary: zinc supplementation in preterm infants could be beneficial in reducing all-cause mortality and in short-term growth and weight curves, but the evidence is scarce. RCTs with adequate design and power would be necessary to recommend their use routinely.

How to cite this article

Ortega Páez E, Flores Villar S. Los suplementos de zinc en prematuros: sin evidencias claras sobre su utilidad. Evid Pediatr. 2021;17:34.

AVC | Critically appraised articles

Staub E, Evers K, Askie LM. Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates. Cochrane Database Syst Rev. 2021;3:CD012797.

Reviewers: Ortega Páez E1, Flores Villar S2.
1Pediatra. UGC de Maracena. Distrito Granada-Metropolitano. Granada. España.
2Unidad de Hospitalización Pediátrica. Hospital Universitario MútuaTerrassa. Barcelona. España.
Correspondence: Eduardo Ortega Páez. Email: edortegap@gmail.com
Reception date: 31/08/2021
Acceptance date: 14/09/2021
Publication date: 29/09/2021

How to cite this article

Ortega Páez E, Flores Villar S. Los suplementos de zinc en prematuros: sin evidencias claras sobre su utilidad. Evid Pediatr. 2021;17:34.

29/09/2021

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