December 2023. Volume 19. Number 4

Eosinophilic esophagitis: long-term treatment dose reduction of proton pump inhibitors is effective

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Gutiérrez Junquera C, Fernández Fernández S, Domínguez Ortega G, Vila Miravet V, García Puig R, La Orden-Izquierdo E, et al. Proton Pump Inhibitor Therapy in Pediatric Eosinophilic Esophagitis: Predictive Factors and Long-Term Step-Down Efficacy. J Pediatr Gastroenterol Nutr. 2023;76(2):191-8.

Reviewers: Lojo Pons P1, González Rodríguez MP2.
1Pediatra. CS Josep Masdevall. Figueres. Girona. España.
2Pediatra. CS Barrio del Pilar. Madrid. España.
Correspondence: Patricia Lojo Pons. Email: patricialojopons@gmail.com
Reception date: 08/11/2023
Acceptance date: 20/11/2023
Publication date: 13/12/2023

Abstract

Authors´ conclusions: the study confirms the efficacy of proton pump inhibitors (PPI) in a large cohort of children with eosinophilic esophagitis (EEo) with sustained histological remission by gradually reducing the drug dose.

Reviewers´ commentary: after long-term treatment with PPI dose reduction in patients with EEo, histological remission is maintained in most cases both at 7 and 16 months.

How to cite this article

Lojo Pons P, González Rodríguez MP. Esofagitis eosinofílica: la reducción de la dosis de tratamiento a largo plazo de los inhibidores de la bomba de protones es efectiva. Evid Pediatr. 2023;19:46.

AVC | Critically appraised articles

Gutiérrez Junquera C, Fernández Fernández S, Domínguez Ortega G, Vila Miravet V, García Puig R, La Orden-Izquierdo E, et al. Proton Pump Inhibitor Therapy in Pediatric Eosinophilic Esophagitis: Predictive Factors and Long-Term Step-Down Efficacy. J Pediatr Gastroenterol Nutr. 2023;76(2):191-8.

Reviewers: Lojo Pons P1, González Rodríguez MP2.
1Pediatra. CS Josep Masdevall. Figueres. Girona. España.
2Pediatra. CS Barrio del Pilar. Madrid. España.
Correspondence: Patricia Lojo Pons. Email: patricialojopons@gmail.com
Reception date: 08/11/2023
Acceptance date: 20/11/2023
Publication date: 13/12/2023

How to cite this article

Lojo Pons P, González Rodríguez MP. Esofagitis eosinofílica: la reducción de la dosis de tratamiento a largo plazo de los inhibidores de la bomba de protones es efectiva. Evid Pediatr. 2023;19:46.

13/12/2023

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