March 2024. Volume 20. Number 1

Tacrolimus in pediatric ulcerative colitis, no news

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Bolia R, Goel A, Semwal P, Srivastava A. Oral tacrolimus in steroid refractory and dependent pediatric ulcerative colitis-A systematic review and meta-analysis. J Pediatr Gastroenterol Nutr. 2023;77:228-34.

Reviewers: Fraile Astorga G1, Molina Arias M2.
1Pediatra. CS Cuellar. Segovia. España.
2Servicio de Gastroenterología Pediátrica. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Garazi Fraile Astorga. Email: garazifraile@hotmail.com
Reception date: 29/12/2023
Acceptance date: 09/01/2024
Publication date: 07/02/2024

Abstract

Authors´ conclusions: tacrolimus has a high initial response in biologic naïve UC children. It can be effectively used as a bridge to other therapies with a 1-year colectomy-free survival of 64%.

Reviewers´ commentary: methodological limitations of this study prevent us from drawing conclusions about the role of tacrolimus treatment in steroid refractory and dependent pediatric ulcerative colitis. We must continue to accept current international recommendations for the treatment of these patients.

How to cite this article

Fraile Astorga G, Molina Arias M. Tacrólimus en el tratamiento de colitis ulcerosa in-fantil, nada nuevo. Evid Pediatr. 2024;20:8.

AVC | Critically appraised articles

Bolia R, Goel A, Semwal P, Srivastava A. Oral tacrolimus in steroid refractory and dependent pediatric ulcerative colitis-A systematic review and meta-analysis. J Pediatr Gastroenterol Nutr. 2023;77:228-34.

Reviewers: Fraile Astorga G1, Molina Arias M2.
1Pediatra. CS Cuellar. Segovia. España.
2Servicio de Gastroenterología Pediátrica. Hospital Infantil Universitario La Paz. Madrid. España.
Correspondence: Garazi Fraile Astorga. Email: garazifraile@hotmail.com
Reception date: 29/12/2023
Acceptance date: 09/01/2024
Publication date: 07/02/2024

How to cite this article

Fraile Astorga G, Molina Arias M. Tacrólimus en el tratamiento de colitis ulcerosa in-fantil, nada nuevo. Evid Pediatr. 2024;20:8.

07/02/2024

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