September 2024. Volume 20. Number 3

A new vaccine in the fight against dengue

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Kallás EG, Cintra MAT, Moreira JA, Patiño EG, Braga PE, Tenório JCV, et al. Live, Attenuated, Tetravalent Butantan-Dengue Vaccine in Children and Adults. N Engl J Med. 2024;390:397-408.

Reviewers: Aizpurua Galdeano P1, Cuestas Montañés EJ2.
1Pediatra de Atención Primaria. San Sebastián. Guipúzcoa. España.
2Servicio de Pediatría y Neonatología. Hospital Privado Universitario de Córdoba. Córdoba. Argentina.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 19/07/2024
Acceptance date: 29/07/2024
Publication date: 04/09/2024

Abstract

Authors´ conclusions: a single dose of Butantan-DV prevented symptomatic DENV-1 and DENV-2, regardless of dengue serostatus at baseline, through 2 years of follow-up.

Reviewers´ commentary: in this study, Butantan-DV has been shown to be effective and safe in the prevention of symptomatic dengue against DENV-1 and DENV-2, even in children 2 years of age or older, regardless of the initial serological status. It looks like a promising vaccine for a disease that is currently a major public health problem in many countries and a threat to others where climatic suitability for dengue is increasing.

How to cite this article

Aizpurua Galdeano P, Cuestas Montañés E. Una nueva vacuna en la lucha contra el dengue. Evid Pediatr. 2024;20:34.

AVC | Critically appraised articles

Kallás EG, Cintra MAT, Moreira JA, Patiño EG, Braga PE, Tenório JCV, et al. Live, Attenuated, Tetravalent Butantan-Dengue Vaccine in Children and Adults. N Engl J Med. 2024;390:397-408.

Reviewers: Aizpurua Galdeano P1, Cuestas Montañés EJ2.
1Pediatra de Atención Primaria. San Sebastián. Guipúzcoa. España.
2Servicio de Pediatría y Neonatología. Hospital Privado Universitario de Córdoba. Córdoba. Argentina.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 19/07/2024
Acceptance date: 29/07/2024
Publication date: 04/09/2024

How to cite this article

Aizpurua Galdeano P, Cuestas Montañés E. Una nueva vacuna en la lucha contra el dengue. Evid Pediatr. 2024;20:34.


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Linked Comment

CA | Análisis de la eficacia y seguridad de una nueva vacuna contra el dengue

Ceballos A. Una nueva vacuna en la lucha contra el dengue. Evid Pediatr. 2024;20:38.