September 2025. Volume 21. Number 3

Vaccination against rotavirus prevents severe gastroenteritis in children under 5 years of age

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Diallo AO, Wikswo ME, Sulemana I, Sahni LC, Boom JA, Ramani S, et al. Rotavirus Vaccine Effectiveness Against Severe Acute Gastroenteritis: 2009-2022. Pediatrics. 2024;154:e2024066879.

Reviewers: Gutiérrez Medina P1, Aparicio Rodrigo M2.
1Pediatra. CS Entrevías. Madrid. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Paloma Gutiérrez Medina. Email: palomagutme@gmail.com
Reception date: 11/09/2025
Acceptance date: 22/09/2025
Publication date: 01/10/2025

Abstract

Authors´ conclusions: rotavirus vaccines are highly effective in preventing emergency department visits or hospitalizations in children aged 8–59 months. Efficacy was highest for more severe disease and conferred protection against common circulating genotypes, even those not included in the vaccine. Effectiveness is highest in children under 3 years of age. These findings highlight the importance of continued investment in routine immunization to prevent severe rotavirus disease in US children.

Reviewers´ commentary: rotavirus vaccines continue to be effective in preventing rotavirus-associated emergency department visits and hospitalizations for the most common genotypes found in this study (G1P8, G2P4, G3P8, G9P8, and G12P8). This study reinforces the importance of continuing to promote high vaccination coverage and monitoring the different genotypes that cause severe infection.

How to cite this article

Gutiérrez Medina P, Aparicio Rodrigo M. Vacunar frente al rotavirus evita gastroenteritis graves en menores de 5 años. Evid Pediatr. 2025;21:33.

AVC | Critically appraised articles

Diallo AO, Wikswo ME, Sulemana I, Sahni LC, Boom JA, Ramani S, et al. Rotavirus Vaccine Effectiveness Against Severe Acute Gastroenteritis: 2009-2022. Pediatrics. 2024;154:e2024066879.

Reviewers: Gutiérrez Medina P1, Aparicio Rodrigo M2.
1Pediatra. CS Entrevías. Madrid. España.
2Pediatra. CS Entrevías. Facultad de Medicina. Universidad Complutense de Madrid. Madrid. España.
Correspondence: Paloma Gutiérrez Medina. Email: palomagutme@gmail.com
Reception date: 11/09/2025
Acceptance date: 22/09/2025
Publication date: 01/10/2025

How to cite this article

Gutiérrez Medina P, Aparicio Rodrigo M. Vacunar frente al rotavirus evita gastroenteritis graves en menores de 5 años. Evid Pediatr. 2025;21:33.

01/10/2025

Linked Comment

Methodological note