September 2008. Volume 4. Number 3

La administración preventiva de Lactobacillus GG al final de la gestación y al lactante no disminuye la presencia de dermatitis atópica en hijos de familias de riesgo

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Kopp MV, Hennemuth I, Heinzmann A, Urbanek R. Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation. Pediatrics. 2008;121:e850-6
Reviewers: Aizpurua Galdeano P1, García Vera C2.
1ABS 7 La Salut Badalona. Badalona. España.
2 Centro de Salud Sagasta-Ruiseñores. Zaragoza. España.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 30/07/2008
Acceptance date: 05/08/2008
Publication date: 01/09/2008

Abstract

Authors’s conclusions: preventive administration of Lactobacillus GG during pregnancy and early infancy did not decrease the incidence of atopic dermatitis and could increase wheezing.

Reviewer’s commentary: even though first investigations looked promising we cannot generally recommend the use of probiotics in the prevention of AD in risk families with actual information. This study has not been able to detect a protective effect of Lactobacillus GG in the prevention of AD but has some limitations. New, well-designed studies are necessary in order to assess the real efficacy of probiotics and prebiotics in the prevention of children’s atopic disease.

How to cite this article

Aizpurua Galdeano P, García Vera C. La administración preventiva de Lactobacillus GG al final de la gestación y al lactante no disminuye la presencia de dermatitis atópica en hijos de familias de riesgo. Evid Pediatr. 2008;4:55.

AVC | Critically appraised articles

Kopp MV, Hennemuth I, Heinzmann A, Urbanek R. Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation. Pediatrics. 2008;121:e850-6
Reviewers: Aizpurua Galdeano P1, García Vera C2.
1ABS 7 La Salut Badalona. Badalona. España.
2 Centro de Salud Sagasta-Ruiseñores. Zaragoza. España.
Correspondence: Pilar Aizpurua Galdeano. Email: 19353pag@gmail.com
Reception date: 30/07/2008
Acceptance date: 05/08/2008
Publication date: 01/09/2008

How to cite this article

Aizpurua Galdeano P, García Vera C. La administración preventiva de Lactobacillus GG al final de la gestación y al lactante no disminuye la presencia de dermatitis atópica en hijos de familias de riesgo. Evid Pediatr. 2008;4:55.

References

  1. Kalliomäki M, Kirjavainen P, Eerola E, Kero P, Salminen S, Isolauri E. Distinct patterns of neonatal gut microflora in infants developing or not developing atopy. J Allergy Clin Immunol. 2001;107:129-34.
  2. Kalliomäki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet. 2001;357:1076-9.
  3. Kukkonen K, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, et al. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol. 2007;119:192-8.
  4. Taylor AL, Dunstan JA, Prescott SL. Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trial. J Allergy Clin Immunol. 2007;119:184-91.
  5. Osborn DA, Sinn JK. Probióticos para la prevención de la enfermedad alérgica y la intolerancia alimentaria en neonatos (Revisión Cochrane traducida). En: La Biblioteca Cochrane Plus, 2008 Número 2. Oxford: Update Software Ltd. Disponible en: http://www.update-software.com. (Traducida de The Cochrane Library, 2008 Issue 2. Chichester, UK: John Wiley & Sons, Ltd.).
01/09/2008

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