June 2011. Volume 7. Number 2

Antibiotic treatment for acute otitis media offer resolution of symptoms approximately one day before

 
 
 
 
 
 
 
 
 
 
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AVC | Critically appraised articles

Hoberman A, Paradise JL, Rockette HE, Shaikh N, Wald ER, Kearney DH et al. Treatment of acute otitis media in children under 2 years of age. N Engl J Med. 2011;364:105-15.
Reviewers: Benito Herreros AM1, Ruiz-Canela Cáceres J2, Martín Muñoz P3.
1EAP Taco - La Laguna. Santa Cruz de Tenerife. España.
2CS Virgen de África. Sevilla. España.
3Director de Unidad Clínica en Atención Primaria, CS La Plata. Hospital Universitario Virgen del Rocí­o. Sevilla. España.
Correspondence: Ana Mª Benito Herreros. Email: anabenitoh@gmail.com
Reception date: 13/04/2011
Acceptance date: 18/05/2011
Publication date: 25/05/2011

Abstract

Authors' conclusion: among children 6 to 23 months of age with acute otitis media, treatment with amoxicillin-clavulanate for 10 days tended to reduce the time to resolution of symptoms and reduced the overall symptom burden and the rate of persistent signs of acute infection on otoscopic examination.

Reviewers' commentary: although authors find differences in symptom scores between the two study groups, they are modest. Adverse effects were more common among the treated group. The number needed-to treat (NNT) is 14, which is higher than the NNT found in other studies performed with amoxicillin, which is nine.

How to cite this article

Benito Herreros AM, Ruiz-Canela CáceresJ, Martín Muñoz P. El tratamiento antibiótico de la otitis media aguda adelanta un día la resolución de los síntomas. Evid Pediatr. 2011;7:30.

AVC | Critically appraised articles

Hoberman A, Paradise JL, Rockette HE, Shaikh N, Wald ER, Kearney DH et al. Treatment of acute otitis media in children under 2 years of age. N Engl J Med. 2011;364:105-15.
Reviewers: Benito Herreros AM1, Ruiz-Canela Cáceres J2, Martín Muñoz P3.
1EAP Taco - La Laguna. Santa Cruz de Tenerife. España.
2CS Virgen de África. Sevilla. España.
3Director de Unidad Clínica en Atención Primaria, CS La Plata. Hospital Universitario Virgen del Rocí­o. Sevilla. España.
Correspondence: Ana Mª Benito Herreros. Email: anabenitoh@gmail.com
Reception date: 13/04/2011
Acceptance date: 18/05/2011
Publication date: 25/05/2011

How to cite this article

Benito Herreros AM, Ruiz-Canela CáceresJ, Martín Muñoz P. El tratamiento antibiótico de la otitis media aguda adelanta un día la resolución de los síntomas. Evid Pediatr. 2011;7:30.

References

  1. Subcommittee on Management of Acute Otitis Media. American Academy of Pediatrics and American Academy of Family Physicians. Clinical Practice Guideline Diagnosis and Management of Acute Otitis Media. Pediatrics. 2004;113:1451-65.
  2. Southern California Evidence-based Practice Center. Management of Acute Otitis Media, Update. Rockville, MD: Agency for Healthcare Research and Quality; 2010. [En línea] [fecha de consulta: 25-I-2011]. Disponible en http://www.ahrq.gov/clinic/tp/otitisuptp.htm
  3. Coker TR, Chan LS, Newberry SJ, Limbos MA, Suttorp MJ, Shekelle PG et al. Diagnosis, microbial epidemiology, and antibiotic treatment of acute otitis media in children: a systematic review. JAMA. 2010;304:2161-9.
  4. Ruiz-Canela Cáceres J, Benito Herreros A, Martín Muñoz P. Otitis media aguda: actualmente siguen siendo válidas las recomendaciones sobre su diagnóstico y tratamiento. Evid Pediatr. 2011;7:16.
  5. Del Castillo Martín F, Delgado Rubio A, Rodrigo G, de Liria C, Villafruela MA, Cervera J et al. Consenso Nacional sobre Otitis Media Aguda. Asociación Española de Pediatría y Sociedad Española de Otorrinolaringología y Patología Cervicofacial. An Pediatr (Barc). 2007;66:603-10.
25/05/2011

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